There is a noticeable difference in the incidence of ventricular arrythmias among patients receiving defibrillator devices (ICD or CRT-D) for primary vs. secondary prevention sudden cardiac death (SCD). The underlying reasons this remain to be fully explained. To assess differences myocardial scar characteristics between who had implanted scenarios, and their correlation with arrhythmic events....

Abstract Background and Aims Mineralocorticoid receptor antagonists (MRA) reduce blood pressure, albuminuria the rate of disease progression in patients with chronic kidney (CKD) albuminuria. Despite these apparent benefits, only a very small fraction CKD are treated an MRA. This may part be due to fear hyperkalemia (HK), which most severe cases can cause life-threatening arrythmias. Indeed, in...

The potential cardiac effects of lamotrigine were added to its label late last year, and in March 2021, FDA released a drug safety communication highlighting the increased risk arrhythmias patients with heart disease who use lamotrigine. Data from vitro testing showed that exhibits Class IB antiarrhythmic activity at therapeutically relevant concentrations. In people structural or myocardial is...

Dear Sir, Brugada syndrome is an inherited arrhythmogenic disease characterized by a typical electrocardiographic pattern consisting of ST-segment elevation in the right precordial leads, and is known to carry a predisposition to sudden cardiac death. Its prevalence is 1–5 per 10,000 inhabitants worldwide. It is responsible for one-fifth of sudden deaths in patients with structurally normal hea...

Ethylenediamine tetraacetic acid, or EDTA, is a synthetic amino acid approved by the FDA for the removal of toxic metal ions such as lead. EDTA is used in isolation for heavy metal poisoning; however, the vast majority of practitioners who offer intravenous EDTA treatments utilize it as a part of a comprehensive therapy program for treating atherosclerosis and other chronic degenerative disease...

The prevalence of Heart Failure (HF) is approximately 1-2% in adult population, rising to more than 10% of elderlies over 70 years of age 1 2. Epidemiological studies show high incidence and prevalence of HF among elderlies. The prognosis of HF in this population is poor with rising cases of hospitalization, comorbidity and health costs 3-5. Cardiac remodeling is a cardinal process mediating th...

Ambulatory ECG (AECG) monitoring with diary correlation of symptoms has been proven to provide significant diagnostic, therapeutic and prognostic benefit an arrhythmic cause symptoms. Arrhythmias can range from premature atrial ventricular complexes (APCs/ PVCs usually benign), Atrial Ventricular Fibrillation which causes morbidity mortality. Symptoms such as palpitations, shortness breath, che...

IN THE current issue of the Journal Cardiothoracic and Vascular Anesthesia, Yao et al. presented a meta-analysis to assess effect etomidate on morbidity mortality in patients undergoing cardiac surgery.1Yao YT He LX Fang NX al.Anesthetic induction with surgical patients: A PRISMA-compliant systematic review meta-analysis.J Cardiothorac Vasc Anesth. 2021; (Accessed 1/4/2021. [e-pub ahead print])...

This article refers to ‘Ventricular tachycardia, premature ventricular contractions, and mortality in unselected patients with lung, colon, or pancreatic cancer: a prospective study’ by M.S. Anker et al., published this issue on pages 145–153. Cardiovascular (CV) disease is increasingly being recognized as an important part of the clinical spectrum cancer, representing second most common cause ...

Surgeons have always been interested in anatomic structures that can be visualized, palpated, dissected and resected. Because lymph nodes have all of these qualitative characteristics, they have attracted the interest of surgeons since the late 19th century. In fact, oncologic signi®cance has been attributed to them and resection has been advocated and even mandated as being an essential compon...