To evaluate whether the 'oxygen and capacity limited thermal tolerance' model (OCLTT) applies to an air-breathing ectothermic vertebrate, we measured oxygen uptake (V̇(O₂)), cardiac performance and arterial blood gases during a progressive rise of temperature from 30 to 40°C in the snake Python regius. V̇(O₂) of fasting snakes increased exponentially with temperature whereas V̇(O₂) of digesting sn...