Polycystic ovary syndrome [PCOS] is associated with abdominal obesity, insulin resistance and dyslipidemia. Women with PCOS may be at an increased risk for the development of type 2 diabetes mellitus. Atherosclerosis is characterised by an inflammatory response of the arterial wall due to endothelial injury. Hence low grade chronic inflammation may independently predict coronary heart disease [...

Dyslipidemia is found to be associated with the initiation and progression of diabetic retinopathy (DR). Modifications of lipoproteins by glycation and oxidation and the variations in the size distributions of lipoprotein particles are not reflected in conventional lipid profiles. This study was conducted to know if the measurements of apolipoprotein AI (apo AI) and apolipoprotein B (apo B) may...

We have analyzed determinants of the synthesis and secretion of apolipoproteins including mRNA for apolipoproteins, in the human colon carcinoma cell line Caco-2 during differentiation in continuous culture. Significant increases in both cellular and secreted apolipoprotein A-I were observed early in the differentiation process. Increases in apolipoprotein B were limited to secreted protein and...