The aim of this study was to identify the flavonoid constituents of the Bulgarian endemic Alchemilla jumrukczalica Pawl. and evaluate the antiradical scavenging activity of the total extract, fractions and individual compounds. The total MeOH extract exhibited a significant DPPH activity (IC50 10.7±0.4 μg/ml), while EtOAc fraction obtained after partition of the total extract was found to be th...

Actinidia arguta fruit (also known as kiwiberry) has a remarkable phytochemical profile, being reported promising preventive agent/treatment for chronic diseases and desirable source of bioactive molecules pharmaceutical cosmetic industries. Despite these indications, investigating the full potential A. remains an unmet need health applications. This work aims to determine optimal extraction co...

Four cultivars (Bronowicka Ostra, Cyklon, Tornado, and Tajfun) of pepper fruit Capsicum annuum L. were studied for phenolics contents and antioxidant activity. Two fractions of phenolics, flavonoids (with phenolic acids) and capsaicinoids, were isolated from the pericarp of pepper fruit at two growth stages (green and red) and were studied for their antioxidant capacity. Both fractions from red...

The oxygen radical absorbance capacity (ORAC) method was used to detect the antiperoxyradical ability of organoselenium compounds: selenophene and its derivative, 2-amino-4,5,6,7-tetrahydro-1-selenophene-3-carbonitrile (ATSe); while as a comparison, the sulfur-containing analogue of selenophene-thiophene and its derivative-2-amino-4,5,6,7-tetrahydro-1-thiophene-3-carbonitrile (ATS)-was selected...

Methanolic extracts from the aerial parts and roots of two Scutellaria species, S. alpina and S. altissima, and five polyphenols from these plants demonstrated a significant ability to inhibit the formation of advanced glycation end-products (AGE) in vitro. S. alpina, which is richer in polyphenolic compounds, had strong antiglycation properties. These extracts demonstrated also high activity i...

Aqueous mixtures of glycerol and 2-hydroxypropyl-β-cyclodextrin (CD), two non-toxic eco-friendly substances, were used as a means of extracting antioxidant polyphenols from oak acorn (Quercur robur) husks. The process was optimized by implementing a central composite (Box-Behnken) experimental design and response surface methodology, taking into consideration the critical parameters (independen...

W. orientalis is a one-year herbaceous plant, located in the Lamiaceae family, and called Ballıbaba Turkish. In presented study, antimicrobial anticancer properties of flowers extracts endemic were investigated for first time. Also, it was antiradical activity phytochemical contents this plant extracts. According to our study results, extract show very high against MCF-7, HCT-116 LNCaP cancer c...