نتایج جستجو برای: antiparasitic activity

تعداد نتایج: 1135284  

Journal: :Clinical Infectious Diseases 2005

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علوم کشاورزی و منابع طبیعی گرگان - دانشکده مرتع و آبخیزداری و شیلات و محیط زیست 1391

جهت بهینه سازی شرایط تولید پروتئین هیدرولیز شده (شامل نسبت آنزیم به سوبسترا، دما و زمان) به منظور دستیابی به بالاترین خواص آنتی اکسیدانی، مینس تهیه شده از ضایعات میگوی ببری سبز (penaeus semisulcatus) پس از تعیین درصد پروتئین آن (13%، بر اساس وزن تر) با استفاده از دو پروتئاز تجاری آلکالاز و فلاورزایم بر اساس 18 تیمار تعیین شده با طرح آزمایشات سطح پاسخ برای هر آنزیم، هیدرولیز شده و با خشک کن انجم...

Journal: :Bioorganic & medicinal chemistry letters 2013
Vicente Castro-Castillo Cristian Suárez-Rozas Adriana Pabón Edwin G Pérez Bruce K Cassels Silvia Blair

Some synthetic 1-azabenzanthrones (7H-dibenzo[de,h]quinolin-7-ones) are weakly to moderately cytotoxic, suggesting that they might also show antiparasitic activity. We have now tested a small collection of these compounds in vitro against a chloroquine-resistant Plasmodium falciparum strain, comparing their cytotoxicity against normal human fibroblasts. Our results indicate that 5-methoxy-1-aza...

Journal: :Molbank 2022

Nitroimidazoles are pharmacophoric groups responsible for important antiparasitic activity against several infectious diseases. 2-Nitroimidazoles found in some drugs and one of the main moieties biological activities exhibited. As an example, we can mention drug benznidazole, only available Brazil treatment Chagas disease. This work describes efficient methodology synthesis 2-nitro-1-vinyl-1H-i...

Journal: :iranian journal of parasitology 0
m tavassoli department of pathobiology, faculty of veterinary medicine, urmia university, urmia, iran a imani department of pathobiology, faculty of veterinary medicine, urmia university, urmia, iran h tajik department of food science and technology, ahar faculty of agriculture, university of tabriz, tabriz, iran m moradi department of food science and technology, ahar faculty of agriculture, university of tabriz, tabriz, iran sh pourseyed department of pathobiology, faculty of veterinary medicine, urmia university, urmia, iran

background : development of new natural agents for parasitic diseases treatment has unexpec­tedly increased to overcome effectively against emergence and re-emergence of parasitic diseases, the appearance of drug resistant organisms and toxic side effects of current agents. the aim of the study was to evaluate antiprotozoal activities of chitosan biomolecule on trophozoites of trichomo­nas gall...

Journal: :Bioorganic & medicinal chemistry 2006
Alice Maria Rolim Bernardino Luiz Carlos da Silva Pinheiro Carlos Rangel Rodrigues Natália Izabel Loureiro Helena Carla Castro Adriana Lanfredi-Rangel Juliano Sabatini-Lopes Júlio César Borges Jane Maria Carvalho Gilberto Alves Romeiro Vitor Francisco Ferreira Izabel C P P Frugulhetti Marcos André Vannier-Santos

In this work, we performed the design, synthesis, and the structure-activity relationship studies of 13 new derivatives of thieno[2,3-b]pyridine. These derivatives were prepared in high yields (96-70%) and their structures were elucidated by IR, (1)H, (13)C NMR, and MS. The biological results showed some derivatives as antiparasitic agents against Giardia lamblia. Computational analysis of HOMO...

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