Epigallocatechin gallate (EGCG) is a main active ingredient in tea, but it difficult for to be absorbed and utilized by the body, resulting limited bioactivity. Therefore, we explored role of probiotics enhancing physiological activity EGCG mice model liver injury. Mice were methodically treated with either single or combination Lactiplantibacillus plantarum P101 (LP.P101) 21 days, then adminis...

Alkylresorcinols (ARs), which are phenolic lipids found in wheat bran, have attracted a considerable amount of attention because their antioxidant properties. However, the mechanism ARs for regulating neuroprotective activity remains unclear. The correlation between cellular effects HT22 cells and vitro were investigated. results showed that two main constituents crude C19:0 C21:0, was identifi...

abstractbackground: radioprotective effects of famotidine, an antagonist of h2 receptor clinically used for peptic ulcer treatment, was previously shown on radiation-induced micronuclei and chromosomal aberration in human peripheral blood lymphocytes and mouse bone marrow cells. this study was conducted to investigate radioprotective property of famotidine against radiation induced apoptosis in...

The researches in the dynamic changes of the progress of HSCs aging are very limited and necessary. In this study, male C57BL/6 mice were divided into 5 groups by age. We found that the superoxide damage of HSPCs started to increase from the middle age (6 months old), with notably reduced antioxidation ability. In accordance with that, the senescence of HSPCs also started from the middle age, s...

Epidemiologic studies suggest a link between infection/inflammation and atherosclerosis. During the acute-phase response to infection and inflammation, cytokines induce tissue and plasma events that lead to changes in lipoprotein. Many of these changes are similar to those proposed to promote atherogenesis. The changes of lipoproteins during infection and inflammation are reviewed with a focus ...

A supported nanoparticle is dynamic in reaction conditions, but how this dynamic behavior is influenced by the support remains elusive. Using the stochastic surface walking global optimization method, herein, we report the structure, thermodynamics and catalytic properties of Pt nanoparticles inside and outside a carbon nanotube (CNT). We reveal that confined metal nanoparticles are, surprising...