نتایج جستجو برای: antinociceptiveanti inflammatoryanticancercelecoxibcox 2 inhibitorthiazolidin 4 ones

تعداد نتایج: 3202935  

2010
M. C. Sharma D. V. Kohli Smita Sharma A. D. Sharma Hari Singh Gaur

An easy and efficient method to obtain Schiff bases of [2-(2-substituted-phenyl)-3-(4-{1-[2-(1Htetrazol-5-yl)-biphenyl-4-ylmethyl])-1H benzoimidazol-2-yl}-phenyl)thiazolidin-4-one] using different aromatic aldehydes. Reaction mixture of Schiff base (0.01 mol) and mercaptoacetic acid (0.05 mol) dissolved in dioxane (50 ml), anhydrous zinc chloride (0.008 mol) was added and refluxed for 12 hrs. T...

Journal: :Molecules 2012
Khaled Toubal Ayada Djafri Abdelkader Chouaih Abdou Talbi

As part of our project devoted to the synthesis of heterocycles including thiazole rings, some new 5-arylidene-2-thioxo-3-N-arylthiazolidin-4-ones were synthesized by Knoevenagel condensation. An interesting feature of these compounds is that their chirality is induced by that of their 3-N-(2-alkyloxyaryl)-2-thioxothiazolidin-4-one precursors, which in turn is due to the presence of a C2 axis o...

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