PURPOSE The comparison of one-site versus two-site phacotrabeculectomy in patients with pseudoexfoliation glaucoma (PEXG) and primary open-angle glaucoma (POAG), with respect to intraocular pressure (IOP), antiglaucomatous medication (AM) requirements and visual acuity (VA). METHODS Forty-seven patients (eyes) with cataract and POAG and 46 sex- and age-matched patients with cataract and PEXG ...

In order to determine the contribution of thymidine (dThd) salvage to intrinsic resistance to antimetabolites (5-fluoropyrimidines, antifolates) in the human colon adenocarcinoma xenograft, H X GC3, a subline deficient in thymidine kinase has been developed. A cell line (GC3/M) was established in continuous culture that demonstrated a karyotype identical to that of the stem line of H X GC3 (46,...

Psicofuranine is a new antibiotic which was first described by Schroeder and Hoeksema (1959), Eble et al. (1959), and Vavra et al. (1959). It has good antibacterial activity in vivo (Lewis et al., 1959) and antitumor activity (Evans and Gray, 1959), but it shows no activity in vitro when assayed by conventional methods. The activity in vitro was demonstrated using the special media and assay te...

IN the last I5 years chemotherapy has come to be recognized as playing an essential part in the palliative management of a few types of malignant disease. The natural and synthetic sex hormones and their derivatives are now in general use in the routine treatment of mammary and prostatic carcinoma; systemic chemotherapy by means of the so-called antimetabolites is the main form of treatment in ...