Abstract Five known compounds (1–5) were isolated from the extract of Mundulea sericea leaves. Similar investigation roots this plant afforded an additional three (6–8). The structures elucidated using NMR spectroscopic and mass spectrometric analyses. absolute configuration 1 was established ECD spectroscopy. In antiplasmodial activity assay, compound showed good with IC50 2.0 μM against chlor...

Infections caused by protozoan parasites continue to be a significant cause of morbidity and mortality across the globe, with malaria leishmaniasis forming fulcrum these infections. Decreased effectiveness existing drugs increasing cases drug resistance have called for multifaceted approach development safe, efficacious, affordable leishmaniasis. The present review article aims unearth structur...

EGFR is a key player in the signalling cascades of various kinds cancers and tyrosine kinase inhibitors block signalling. Natural products have long been used as candidates for therapy management cancer. Violacein, bacterial pigment, has known its numerous biological applications such antimicrobial, antileishmanial, antiviral, well antitumoral. Computational studies concluded that it may activi...