OBJECTIVES Guidelines to treat acute otitis media (AOM) were published in 2004. Initial declines in prescribing were shown, but it's unknown if they were sustained. We examine trends in antibiotic dispensing patterns to treat AOM among a large population of children. We also document trends in antibiotic failure. STUDY DESIGN Children aged 3 months to 12 years with an AOM diagnosis, enrolled ...

BACKGROUND Antibiotic resistance is a rising problem in Malaysia. For instance, high antibiotic prescribing rate for upper respiratory tract infection and inappropriate choice of antibiotic is a significant healthcare concern in Malaysia. Our main objective was to study knowledge, attitude and practice of antibiotic prescribing among medical officers in Kedah, Malaysia. METHODS A cross sectio...

INTRODUCTION The common occurrence of infectious diseases in nursing homes and residential care facilities may result in substantial antibiotic use, and consequently antibiotic resistance. Focusing on these settings, this article aims to provide a comprehensive overview of the literature available on antibiotic use, antibiotic resistance, and strategies to reduce antibiotic resistance. METHOD...

BACKGROUND Antibiotic homogeneity is thought to drive resistance but in vivo data are lacking. In this study, we determined the impact of antibiotic homogeneity per se, and of cefepime versus antipseudomonal penicillin/β-lactamase inhibitor combinations (APP-β), on the likelihood of infection or colonisation with antibiotic resistant bacteria and/or two commonly resistant nosocomial pathogens (...

BACKGROUND The incidence of bacteremia caused by Gram-negative bacteria has increased recently in febrile neutropenic patients with the increase of antibiotic-resistant Gram-negative bacterial infections. This study aimed to identify the distribution of causative bacteria and the proportion of antibiotic-resistant bacteria in bacteremia diagnosed in febrile neutropenic children. MATERIALS AND...

abstract: so far, too little attention has been paid to total burden of healthcare associated infections (hais) in iran. in present study, we aimed to assess the rate of hais, as well as economic burden of hospitalization and antibiotic related cost associated with hais at training taleghani hospital in iran and to compare our results with nnis system. this research to date for the first time h...

objective bacterial adhesion is governed by specific and nonspecific interactions such as hydrophobicity. hydrophobic interactions play a role in the adherence of microorganisms to a wide variety of surfaces and facilitate biofilm formation due to bacterial adhesion. in this article the relation between cell surface hydrophobicity and antibiotic resistance was studied. materials and methods we ...

1. Appreciate the implications of antibiotic resistance. 2. Understand the mechanisms of antibiotic resistance. 3. Understand which factors contribute to the emergence of antibiotic resistance. 4. Understand the important role of the pharmacist in the era of antibiotic resistance.

background and objective: urinary tract infections (utis) are the most common infections in renal transplant recipients and are considered a potential cause of bacteremia, sepsis, and affects graft outcomes. the aim of the present study was to determine the incidence of uti among renal transplant recipients and investigation of antimicrobial susceptibility pattern of causative agents. materials...

background and objectives : salmonella is one of the leading causes of food-borne diseases. increasing occurrence of antimicrobial resistance, especially multidrug-resistance, in salmonella serovars is a major public health problem worldwide. this study was carried out to detect class i integrons and antibiotic resistance profiles in clinical isolates of salmonella serovars collected from seven...