conclusions the results of this study indicated that a decrease in oprd gene expression is an important mechanism of resistance in carbapenem resistant pseudomonas aeruginosa isolated from severe burn patients with secondary infection. results our study showed that 94.2% of the isolates were resistant to imipenem, 99.5% to meropenem, and all were resistant to ertapenem. the oprd gene expression...

background: campylobacter infections may lead to serious conditions, including septicemia or other invasive forms of the disease, which require rapid and accurate laboratory diagnosis and subsequently appropriate antimicrobial therapy. the aim of this study was to compare the species distribution and antimicrobial susceptibility pattern of campylobacter spp. strains isolated from patients and f...

Gram-positive bacteria are formidable human pathogens. Staphylococci are responsible for more than a million hospital-acquired bacterial infections every year. Streptococcus pneumoniae is responsible for a major portion of 3 million deaths worldwide of children from pneumonia and meningitis and for a large number of deaths from pneumonia that occurs in elderly individuals. In addition, individu...

background: multidrug resistance and production of extended spectrum β-lactamases (esbls) by enteric gram-negative rods in hospitals and community continue to be worsened. we aimed to characterize the multidrug resistance and determine the prevalence of esbl production by clinical isolates of enterobacteriaceae in southeast iran.   methods: gram-negative bacteria isolated from clinical samples ...

The present study was designed to analyze the difference of the adeB gene expression levels under conditions of induced resistance and to verify the significance of the AdeABC efflux pump in the in vitro induction of Acinetobacter baumannii (A. baumannii). Strains were isolated from blood or drainage samples in the First Hospital of China Medical University. The minimum inhibitory concentration...

conclusions in this study, like previous researches, e. coli was the most common pathogen. our results suggested a high rate of antibiotic resistance to common antibiotics for treatment of uti. because of the high resistance to cephalexin, cefotaxime and co-trimoxazole, their use is not recommended for treatment of utis. imipenem and vancomycin were the most active drugs against e. coli and sta...

background staphylococcus aureus is a significant pathogen that can colonize the nares of different animals, causing a wide range of infections in various hosts. objectives we intended to determine the prevalence of s. aureus in the nasal cavity of healthy ruminants and also to investigate the presence of antibiotic resistance genes. materials and methods in the present study, healthy cattle (n...

conclusions induction of coccoid form of p. aeruginosa may be one of the important reasons for antibiotic treatment failure; therefore, prescribed dose of antibiotics should be carefully managed to prevent increasing antibiotic resistance and coccoid bacteria induction. results all used antibiotics at sub mic concentration had capability to induce coccoid bacteria. the highest rate of induced c...