نتایج جستجو برای: anti biofilm

تعداد نتایج: 384868  

Journal: :International journal of antimicrobial agents 2004
Peter Tenke Claus R Riedl Gwennan Ll Jones Gareth J Williams David Stickler Elisabeth Nagy

In the process of endourological development a variety of foreign bodies have been invented besides urinary catheters, on which biofilm can be formed. Bacteria in the biofilm are less susceptible to antibiotics. An additional problem of medical biomaterials in the urinary tract environment is the development of encrustation and consecutive obstruction. The most promising prevention strategy for...

Journal: :Molecular bioSystems 2008
Robert W Huigens Luyan Ma Christopher Gambino Peter D R Moeller Anne Basso John Cavanagh Daniel J Wozniak Christian Melander

Bacterial biofilms are defined as a community of surface-attached bacteria that are protected by an extracellular matrix of biomolecules. We have recently reported the synthesis of a small molecule, denoted TAGE, based on the natural product bromoageliferin and demonstrated that TAGE has anti-biofilm activity against Pseudomonas aeruginosa. Herein we demonstrate that TAGE: (1) does not have sel...

Journal: :Postdoc journal : a journal of postdoctoral research and postdoctoral affairs 2015
César de la Fuente-Núñez Robert E W Hancock

Host defense (antimicrobial) peptides (HDPs) are produced by virtually all organisms and have an important role in protection against microbial infections. Some naturally occurring peptides such as the human cathelicidin LL-37 and the bovine peptide indolicidin have been shown to inhibit bacterial biofilm development. Rearrangement and substantial modification of the amino acid sequence of thes...

Journal: :Jurnal Kedokteran Gigi Terpadu 2023

Background: Enterococcus faecalis biofilm is one of the causes root canal treatment failure. The success achieved by mechanical and chemical functions. Irrigation only way to reach areas wall that instrumentation cannot reach. Guava (Psidium guajava Linn.) leaves contain compounds such as flavonoids, saponins, tannins, triterpenoids essential oils which have antibacterial properties. Objective:...

2017
Hao Guo Ziming Wang Quanyin Du Pan Li Zhigang Wang Aimin Wang

PURPOSE Bacterial biofilms on the surface of prostheses are becoming a rising concern in managing prosthetic joint infections. The inherent resistant features of biofilms render traditional antimicrobial therapy unproductive and revision surgery outcomes uncertain. This situation has prompted the exploration of novel antimicrobial strategies. The synergy of ultrasound microbubbles and vancomyci...

Journal: :Frontiers in microbiology 2015
Yu-Feng Zhou Wei Shi Yang Yu Meng-Ting Tao Yan Q. Xiong Jian Sun Ya-Hong Liu

Biofilm formations play an important role in Staphylococcus aureus pathogenesis and contribute to antibiotic treatment failures in biofilm-associated infections. The aim of this study was to evaluate the pharmacokinetic/pharmacodynamic (PK/PD) profiles of cefquinome against an experimental catheter-related biofilm model due to S. aureus, including three clinical isolates and one non-clinical is...

J. Safari M. Khoobi, M. Pourhajibagher Sh. Farkhonde Masoule

Root canal disinfection is one of the main factors governing success of endodontic therapy. Antimicrobial photodynamic therapy (aPDT) is presented as a promising antimicrobial therapy that can eliminate microbiota present in infected root canal systems. In this study, a series of experiments investigated the effects of aPDT on cell viability and biofilm degradation ability of endopathogenic mic...

Journal: :Journal of bacteriology 2009
Nekane Merino Alejandro Toledo-Arana Marta Vergara-Irigaray Jaione Valle Cristina Solano Enrique Calvo Juan Antonio Lopez Timothy J Foster José R Penadés Iñigo Lasa

The capacity of Staphylococcus aureus to form biofilms on host tissues and implanted medical devices is one of the major virulence traits underlying persistent and chronic infections. The matrix in which S. aureus cells are encased in a biofilm often consists of the polysaccharide intercellular adhesin (PIA) or poly-N-acetyl glucosamine (PNAG). However, surface proteins capable of promoting bio...

Journal: :The Journal of antimicrobial chemotherapy 2012
Stephanie Baugh Aruna S Ekanayaka Laura J V Piddock Mark A Webber

OBJECTIVES To investigate the contribution of multidrug efflux pump systems of Salmonella enterica serovar Typhimurium to the formation of a competent biofilm. METHODS Biofilm formation by a wild-type strain and 10 efflux mutant strains was quantified using crystal violet biofilm assays and visualized using scanning electron microscopy. Curli expression was investigated qualitatively and quan...

Journal: :Journal of oral science 2009
Yanti Yaya Rukayadi Kwan-Hyoung Lee Jae-Kwan Hwang

The formation of dental biofilm caused by oral bacteria on tooth surfaces is the primary step leading to oral diseases. This study was performed to investigate the preventive and reducing effects of panduratin A, isolated from Kaempferia pandurata Roxb., against multi-species oral biofilms consisting of Streptococcus mutans, Streptococcus sanguis and Actinomyces viscosus. Minimum inhibitory con...

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