The anthraquinones, doxorubicin, mitoxantrone, daunorubicin and rubidazone are shown to be potent stimulators of Ca2+ release from skeletal muscle sarcoplasmic reticulum (SR) vesicles and to trigger transient contractions in chemically skinned psoas muscle fibers. These effects of anthraquinones are the direct consequence of their specific interaction with the [3H] ryanodine receptor complex, w...

The crystal structure of the telomeric sequence d(UBrAGG) interacting with an anthraquinone derivative has been solved by MAD. In all previously studied complexes of intercalating drugs, the drug is usually sandwiched between two DNA base pairs. Instead, the present structure looks like a crystal of stacked anthraquinone molecules in which isolated base pairs are intercalated. Unusual base pair...

The title mol-ecule, C(28)H(20)O(8)S(2), has a T-shaped conformation. The central 9,10-anthraquinone moiety is bow-shaped with the two outer aromatic rings being inclined to one another by 13.99 (11)°. The benzenesulfonate rings are inclined to one another by 47.35 (12)°, and by 34.51 (11) and 17.88 (11)° to the bridging aromatic ring of the 9,10-anthraquinone moiety. In the crystal, C-H⋯O inte...

Topoisomerase II (Top-II) is an essential therapeutic target in cancer treatment owing to its overexpression a wide variety of cancerous cells, including colorectal and breast cancer. Significant efforts have been made discover develop competitive inhibitors the Top-II enzyme as potential anticancer agents. Herein, molecular modeling was employed identify new series furyl-2-carboxamide derivati...

Polycyclic aromatic hydrocarbons (PAHs) are known to exhibit photoinduced toxicity to organisms, especially in the presence of ultraviolet irradiation. Oxidation is the most common photochemical reaction of anthracene (ANT) and ANT derivatives. Quinones, hydroxy-quinones, diols, and aldehydes are the resultant products. Different ANT photoproducts have different impact on biological organisms. ...

In this paper, we elucidated the observational changes in conductance of different anthracene derivatives namely anthracene, anthraquinone, anthracenediamine and anthracencedithiol through two-terminal molecular junctions at room temperature. The main purpose of this work was to show varying impacts of interference phenomena in anthracene molecule stringed to two identical electrodes by differe...

We have reported here a simple, low cost preparation of four new adducts from some anthraquinone disperse dyes with functionalized multi-walled carbon nanotubes in the presence of azochromophore. The structural differences between the final products are evaluated by visual dispersion test, UV-Vis Spectroscopy, Fourier transforms infrared, Raman, nuclear magnetic resonance and thermal gravimetri...