[Purpose] The purpose of this study is to research the most effective knee flexion angle and ground condition in the squat position. [Subjects and Methods] The subjects of this study were 15 female college students who were able to perform squat movements and who had never previously experienced surgery, orthopedic disease, or musculoskeletal impairment. This study was conducted to examine chan...

The purpose of the present study was to investigate the effect of cadence on joint specific power and cycling kinematics in the ankle joint in addition to muscle oxygenation and muscle VO2 in the gastrocnemius and tibialis anterior. Thirteen cyclists cycled at a cadence of 60, 70, 80, 90, 100 and 110 rpm at a constant external work rate of 160.1 ± 21.3 W. Increasing cadence led to a decrease in...

The aim of the study was to test whether the considerable differences in the hindlimb muscles mass, the number and diameter of muscles fibers were connected with differences in the myosin heavy chain isoform content (expressed as the percentage of the given isoform in respect to total myosin heavy chains). Therefore, the content of myosin heavy chain (MHC) isoforms was studied in four hindlimb ...

The IFN-alpha cytokines belong to a multigene family. However, the in vivo biological functions of each of the IFN-alpha subtypes is unknown. Recently, we developed an experimental model in which the tibialis anterior muscles of mice were transfected in situ with naked DNA plasmids encoding an IFN transgene. Here we use this model to investigate the in vivo effect of the expression of three mur...

The Akt substrate of 160 kDa (AS160) is phosphorylated on Akt substrate (PAS) motifs in response to insulin and contraction in skeletal muscle, regulating glucose uptake. Here we discovered a dissociation between AS160 protein expression and apparent AS160 PAS phosphorylation among soleus, tibialis anterior, and extensor digitorum longus muscles. Immunodepletion of AS160 in tibialis anterior mu...

The AMP-activated protein kinase (AMPK) acts as a fuel gauge during exercise and stress-induced energy crisis. The function of the masseter muscle changes during postnatal development, along with an alteration in type of muscle fiber. We investigated expression of AMPK subunit isoforms in masseter muscle by quantitative real-time RT-PCR and Western blotting, and compared it with that in tibiali...