Background: Posterior sagittal anorectoplasty (PSARP) is the newest and most-widely-used technique for correction of anorectal malformations (ARMs). In the present investigation, the functional outcomes of PSARP and also the relationship between the complications and the sacral ratio (SR) have been studied. Methods: The study group included 49 patients (25 males and 24 females) with ARMs, opera...

OBJECTIVE The patients with anorectal malformations (ARM) have been identified with specific and non-specific pathological changes. The present study was conducted with the aim to study histomorphological changes and various immunohistochemical (IHC) markers (calretinin, S-100, CD117) in intestinal wall specimens to assess neuronal dysfunction in ARM patients. MATERIAL AND METHODS Thirty chil...

Diamond-Blackfan anemia (DBA) is caused mainly by genetic mutations in large (RPL) or small ribosomal subunit genes (RPS) and presents with macrocytic congenital malformations. Clinical differences between genotypes are insufficiently understood. The aim of this study was to assess clinical features, treatment strategies, the Swiss pediatric DBA population. We retrospectively reviewed medical c...

Anorectal malformations in girls include a wide range of abnormalities, from the non-perforated anal membrane to cloaca. The most common is rectovestibular fistula. Purpose - improve results surgical treatment congenital anorectal with fistula using differentiated approach choice tactics. Materials and methods. A comprehensive examination children was performed. Associated diagnosed this type a...

Abstract Background A colostomy is a surgical approach that creates an opening for the colon, or/and large intestine through abdomen. Anorectal malformations are group of abnormalities rectum and anus present at birth. Objective To analyze common complications in anorectal formations. Methods This was retrospective study conducted on 50 temporary colostomies performed children Surgical Departme...