A methylene chloride extract of the pulp of Annona muricata L. was fractionated in search for scarcely functionalized Annonaceous acetogenins (type E). Previously known C-35 and C-37 mono-epoxy unsaturated compounds, epomuricenins-A and -B (1+2) and epomusenins-A and -B (3+4), were obtained. Two new mono-epoxy saturated C-35 representatives, epomurinins-A and -B (5+6) were also isolated.

Los ecosistemas tropicales tienen altas limitaciones en la disponibilidad natural de fósforo el suelo, condición que se intensifica con su pérdida y fragmentación. En paisajes modificados, relación entre árboles aislados precipitación puede representar una entrada PO₄-P al suelo. Este estudio realiza mediciones sobre 16 individuos 4 especies aislados: Cariniana pyriformis, Cedrela odorata, Lueh...

Introducción: en la actualidad el uso de productos naturales son una opción tratamiento diversas enfermedades, como bien podría ser oleorresina copaiba, que presenta propiedades podrían usadas un coadyuvante periodontitis. Objetivo: determinar efecto clínico y antibacteriano Copaifera reticulata (C. reticulata) «copaiba» apoyo a terapia periodontal no quirúrgica (TPNQ) periodontitis pacientes d...

A total synthesis of annonacin (1) was accomplished by using versatile chiral building block 2 for synthesizing the mono-tetrahydrofuran (THF) annonaceous acetogenins.

The hepatoprotective effect of Annona muricata and Polyalthia cerasoides (Annonaceae) were monitored by estimating the serum transaminases (SGOT and SGPT), serum alkaline phosphatase (SALP), liver and brain lipid peroxidation (LOP) and their total protein content. Both drugs at a dose of 100 μg/kg significantly prevented the increase in serum transaminases, SALP, liver and brain LOP and decreas...

Four novel mono-tetrahydrofuran (THF) acetogenins, montanacins B-E (1-4), were isolated from the ethanolic extract of the leaves of Annona montana. The structures of 1-4 were established by spectroscopic methods and their absolute stereochemistries were determined by the advanced Mosher ester method. Montancins D (3) and E (4) bear a non-adjacent tetrahydropyran (THP) ring along with a THF ring...