The sugar alcohol meglumine enhances the solubility of organic compounds in water and enforces formation electron donor–acceptor (EDA) complexes, enabling photochemical C−C C−S cross-coupling transformations without sensitizers. light-driven redox-neutral protocol connects haloarenes with indoles, anilines, anisoles, thiols, as reported by Burkhard König co-workers their Research Article (e2022...

A N-methyl-2-pyrrolidonium hydrogensulfate [NMP][HSO4] bronsted acidic ionic liquid-promoted cyclocondensation-cyclization pathway has been established using one pot reaction of anilines, aldehydes and mercaptoacetic acid to give 4-thiazolidinone derivatives in good promising yields microwave irradiation. Applications for this protocol are easy workup, high yields, short times, variability func...

The gem-aminoalkynylation of fluorinated diazo compounds catalyzed by a simple Cu(I) salt is described. This three-component reaction allows the synthesis propargylic amines with broad functional group tolerance. Both electron-rich and electron-poor anilines can be used as nucleophiles alkyl-, aryl-, silyl-substituted EthynylBenziodoXoles (EBX) electrophiles.

Quantum chemical modeling was used to investigate the electron-donating properties of the amino group in a series of meta- and para-X-substituted anilines (X = NMe2, NH2, OH, OMe, CH3, H, F, Cl, CF3, CN, CHO, COMe, CONH2, COOH, NO2, and NO). Different methods (HF, B3LYP, and M06-2X) and basis sets (6-31+G(d,p), 6-311++G(d,p), and aug-cc-pVDZ) were applied and compared with the MP2 approach. The...

Abstract Herein, we report a new one-step direct synthesis of aromatic azo compounds from anilines under mild conditions. With the catalysis copper acetate mediated by palladium salt, rapid conversion to can be observed conditions base-free along with solvent-free. Furthermore, cross-coupling nitridation reaction based on this strategy was also studied. This research provides not only way for s...

The development of a stereoselective aza-Piancatelli reaction to access 4-aminocyclopentenones is reported. This transformation relies on the use chiral o-sulfinyl anilines as inductors afford targeted products in good excellent yields. Remarkably, high value-added cyclopentenones could be obtained drs up >95:5, depending upon furan substitution pattern.