In the present study, Chitosan microspheres containing Trospium chloride were prepared by coacervation phase separation method and characterized by optical microscopy and scanning electron microscopy. The microspheres were analyzed for drug entrapment, bulk density, angle of repose, particle size and In-vitro release pattern. The effect of process variables on microsphere size was studied and b...

Sustained release tablets of Diclofenac Sodium were fabricated using Cashew nut tree gum, HPMC and Carbopol . The tablets were evaluated for preformulation studies like angle of repose, bluk density, compressibility index and physical characteristics like hardness, weight variation, fraibilty and drug content. In-vitro release of drug was performed in PBS pH 7.2 for twelve hours. All the physic...

This study was undertaken to explore gum from Bombax buonopozense calyxes as a binding agent in formulation of immediate release dosage forms using wet granulation method. The granules were characterized to assess the flow and compression properties and when compressed, non-compendial and compendial tests were undertaken to assess the tablet properties for tablets prepared with bombax gum in co...

Tizanidine HCl is a centrally acting α-2 adrenergic agonist muscle relaxant. It is slightly bitter in taste. In the present study an attempt has been made to prepare bitterless fast dissolving tablet of Tizanidine Hydrochloride using Eudragit E 100 as a taste masking agent. Mass extrusion was the technique used for preparing taste masked granules. The tablet was prepared with three super disint...

Granular solid hydrodynamics (GSH) is a continuum-mechanical theory for granular media, whose wide range of applicability is shown in this paper. Simple, frequently analytic solutions are related to classic observations at different shear rates, including: i) static stress distribution, clogging; ii) elasto-plastic motion: loading and unloading, approach to the critical state, angle of stabilit...

nowadays, we live in a world which quality, speed, accuracy and cost are the most important parameters in parts' design and manufacturing. due to the complexity of part manufacturing, traditional and nontraditional manufacturing techniques are used. aerodynamic tests usually requires one or several models for testing in wind tunnels and these models typically have particular complexities in whi...

So, what happens in this encounter of mind and being? What kind of agency does the moment of repose initiate? What does it mean to confront the possible and the real in this instant? Why is the mind only present in this encounter that takes place within the moment of repose? And why, for Bachelard, is the initiation of an action the origin of a temporal duration? Why is temporality only an effe...

The objective of the study was to determine geometric, gravimetric, aerodynamic, and frictional properties maize grain as affected by varietal differences moisture content. Honampa, Omankwa, Abontem, Timtim, Obatanpa were five varieties studied. Moisture content, geometric properties, gravimetric aerodynamic mean diameters ranged between 6.65 7.55 mm, while projected areas 52.98 73.12 m2. surfa...