OBJECTIVE The aim was to define the long term prognosis of isolated ventricular septal defect (VSD) with anteriorly malaligned outlet septum. DESIGN Cohort study. SETTING University hospital, tertiary medical care centre. PATIENTS Between July 1986 and June 1993, 63 patients were studied with an isolated VSD and anteriorly malaligned outlet septum (59 perimembranous; 4 muscular outlet). ...

Past statistical studies demonstrating the likelihood of slow blood flow in most ruptured aneurysms have suggested that thrombogenesis plays an important role in ruptures of cerebral artery aneurysms. In the authors’ previous study, it was reported that the degree of platelet aggregation in an aneurysm had a significant correlation with the flow pattern in the aneurysmal dome. It is, therefore,...

OBJECTIVE Acquiring contemporary data on prevalence and natural history of abdominal aortic aneurysms (AAA) is essential in the effort to optimise modern screening programmes. The primary aim of this study was to determine the fate of a 65-year-old male population 5 years following an invitation to an aortic ultrasound (US) examination. METHODS In this population-based cohort-study, men were ...

BACKGROUND AND PURPOSE The middle cerebral artery (MCA) bifurcation is a preferred site for aneurysm formation. Wider bifurcation angles have been correlated with increased risk of aneurysm formation. We hypothesized a link between the presence of MCA aneurysms and the angle morphology of the bifurcation. METHODS Three-dimensional rotational angiography volumes of 146 MCA bifurcations (62 ane...

BACKGROUND AND PURPOSE A single-center prospective randomized controlled trial has been conducted to determine if lumbar drainage of cerebrospinal fluid after aneurysmal subarachnoid hemorrhage reduces the prevalence of delayed ischemic neurological deficit and improves clinical outcome. METHODS Patients with World Federation of Neurological Surgeons Grade 1 to 3 aneurysmal subarachnoid hemor...

BACKGROUND AND PURPOSE The purpose of this study was to analyze angiographic and clinical results before and after additional endovascular therapy in patients with previously coiled but reopened cerebral aneurysms and to identify possible risk factors for retreatment of an aneurysm. MATERIALS AND METHODS Follow-up with selective digital subtraction angiography was performed in 323/596 (54.2%)...

BACKGROUND AND PURPOSE The morbidity and mortality of subarachnoid hemorrhage (SAH) are high, and established risk factors are scarce. We prospectively assessed the association of blood pressure, smoking, and body mass with the risk of aneurysmal SAH. METHODS All residents >or=20 years were invited to the Nord-Trøndelag Health (HUNT) Study (1984 to 1986) and 74,977 (88.1%) attended. The study...

BACKGROUND AND PURPOSE Delayed cerebral ischemia is a significant cause of morbidity and mortality after aneurysmal SAH, leading to poor outcomes. The purpose of this study was to evaluate the usefulness of CTP in determining delayed cerebral ischemia in patients with aneurysmal SAH. MATERIALS AND METHODS We conducted a systematic review evaluating studies that assessed CTP in patients with a...

Tortuous aneurysmal arteries are often associated with a higher risk of rupture but the mechanism remains unclear. The goal of this study was to analyze the buckling and post-buckling behaviors of aneurysmal arteries under pulsatile flow. To accomplish this goal, we analyzed the buckling behavior of model carotid and abdominal aorta with aneurysms by utilizing fluid-structure interaction (FSI) ...