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Phosphatidylinositol 3-kinase (PI3K) promotes cell survival and communication by activating its downstream effector Akt kinase. Here we show that PS1, a protein involved in familial Alzheimer's disease (FAD), promotes cell survival by activating the PI3K/Akt cell survival signaling. This function of PS1 is unaffected by gamma-secretase inhibitors. Pharmacological and genetic evidence indicates ...
this research concentrates on the lithostratigraphy, biostratigraphy, microfacies and sedimentary environment of the asmari and gachsaran formations at southwest firuzabad. the thickness of the studied section in all 608.95 meters that 220.8 meters belong to the asmari formation and 387.95 meters belong to the gachsaran formation (champe and mol members). in the study area, the asmari formation...
abstract birbery and corruption and other criminal and as such is one of social phenomena , and i can firmly say that society is protected and safe from harm , this is criminal . eache community is familiar with these crimes and the crime associated ( direct or indirect ) with the political economic , social , and cultural beliefs and religious issues , especially with the community . admitted...
this dissertation has six chapter and tree appendices. chapter 1 introduces the thesis proposal including description of problem, key questions, hypothesis, backgrounds and review of literature, research objectives, methodology and theoretical concepts (key terms) taken the literature and facilitate an understanding of national security, national interest and turkish- israeli relations concepts...
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