Ecological factors generally affect population viability on rapid time scales. Traditional population viability analyses (PVA) therefore focus on alleviating ecological pressures, discounting potential evolutionary impacts on individual phenotypes. Recent studies of evolutionary rescue (ER) focus on cases in which severe, environmentally induced population bottlenecks trigger a rapid evolutiona...

Background: The aim of this study was to evaluate protective effects of melatonin on uterus and fallopian tube in female mice under treatment with nicotine. Materials and Methods: Adult Female mice were divided into four groups. Group A: control animals received normal saline, group B: were injected with nicotine 40 μg/kg. Group C:were injected with melatonin, 10 μg/ night. Group D:were injecte...

Although protein-folding stress at the endoplasmic reticulum (ER) is emerging as a driver of neuronal dysfunction in models of spinal cord injury and neurodegeneration, the contribution of this pathway to peripheral nerve damage remains poorly explored. Here we targeted the unfolded protein response (UPR), an adaptive reaction against ER stress, in mouse models of sciatic nerve injury and found...

BACKGROUND Rehabilitation improves recovery after intracerebral hemorrhage (ICH) caused by collagenase infusion into the striatum of rats by promoting dendritic growth and reducing brain injury in this model. OBJECTIVE Effective preclinical testing requires multiple models because none, including the collagenase model, perfectly mimics human ICH. Thus, the authors assessed enhanced rehabilita...

recently, biological fertilizers extensively recommended because of over application of chemical fertilizer and their effects on environment and production resources. in order to study the effect of inoculate phosphate solubilization microorganisms (psm) and plant growth promoting rhizobacteria (pgpr) on nutrient use efficiency in corn [zea mays (l.) cv. sc 604] an experiment was conducted in 2...

BACKGROUND After perinatal brain injury, clinico-anatomic correlations of functional deficits and brain plasticity remain difficult to evaluate clinically in the young infant. Thus, new non-invasive methods capable of early functional diagnosis are needed in young infants. CASE PRESENTATION The visual system recovery in an infant with perinatal stroke is assessed by combining diffusion tensor...

xanthomonas campestris pv.musacrearum causes banana wilt disease (bxw disease) which occurs at different epidemic phases in east and central africa (eca). in the endemic areas, there are many banana fields with over 80% bxw disease incidence. this study aimed at rehabilitating banana fields heavily infected with bxw disease in uganda, kenya and dr. congo. farmer managed trials were established ...

Background: Histone deacetylation of tumor suppressor genes such as estrogen receptor alpha (ERα) can induce cancer, which is reversible by epi-drugs such as valproic acid (VPA). The previous result indicated that tamoxifen (TAM) induced apoptosis in hepatocellular carcinoma (HCC). This study was designed to assess the apoptotic and antiproliferative effects of VPA and TAM and also the ef...

Electrochemical study of Er(III)/Er and Yb(III)/Yb systems was independently investigated in molten LiF-CaF2 on inert electrode at 840 °C using cyclic voltammetry square wave voltammetry. Experimental results showed that two different behaviours were observed: Er(III) reduced into metal a one-step diffusion controlled process Yb(III) first Yb(II) then Yb. The electrochemical containing both Mo ...

Numerous secretory and membrane proteins undergo post-translational modifications in the endoplasmic reticulum (ER), and the formation of disulfide bonds is a modification that is critical for proper protein folding. The mammalian ER contains a large family of oxidoreductases that are considered to catalyze thiol/disulfide exchange and ensure the maintenance of a redox environment within the ER...