Background: Despite modern developments in its management, still major concerns remain about drug resistance in chemotherapy. Natural adjuvants combined with chemotherapy might be the answer. We examined the anti-cancer, anti-proliferative and synergistic effects of Sambucus nigra extract with cisplatin chemotherapy (CDDP) on MCF-7 and MDA-MB-231 human cancer cell lines. Methods: MCF-7 and MDA...

In this paper, the ability of coconut bunch waste (CBW), an agricultural waste available in large quantity in Malaysia, to remove basic dye (methylene blue) from aqueous solution by adsorption was studied. Batch mode experiments were conducted at 30 degrees C to study the effects of pH and initial concentration of methylene blue (MB). Equilibrium adsorption isotherms and kinetics were investiga...

The available shock-wave data for solid .a quartz in the stishovite pressure regime are reduced to a 25øC isotherm and an adiabat, centered at standard conditions, using recent standard density, enthalpy, and coefficient of thermal expansion data. The calculated isothermal bulk modulus, 3 Mb, as determined from the Bireh-Murnaghan equation, depends critically on the value of (dK/dP)•, at zero p...

background: the cardiac effects simultaneously occurring during experimental hypertension and diabetes have rarely been investigated. this study aimed at examining the effects of short-term renovascular hypertension and type 2 diabetes on cardiac functions. methods: five groups (7 each) of male sprague-dawley rats, including a control group, a diabetes (induced by streptozocin and nicotinamide)...

‎The sequences of the form ${E_{mb}g_{n}}_{m‎, ‎ninmathbb{Z}}$,‎ ‎where $E_{mb}$ is the modulation operator‎, ‎$b>0$ and $g_{n}$ is the‎ ‎window function in $L^{2}(mathbb{R})$‎, ‎construct Fourier-like‎ ‎systems‎. ‎We try to consider some sufficient conditions on the window‎ ‎functions of Fourier-like systems‎, ‎to make a frame and find a dual‎ ‎frame with the same structure‎. ‎We also extend t...

background: breast cancer is the most common diagnosed cancer among women in the world. snail1 plays a role in the development of the invasive phenotypes of cancer, neural cell differentiation, cell division and apoptosis in tumor cells. traces of snail1 in metastasis of breast cancer to bone are observed. the aim of this study was to investigate the effect of specific snail1 sirnas on the prol...

Abstract The polymer inclusion membranes (PIMs) containing Cellulose triacetate as base, 2-NPOE a plasticizer, and Calix[4]resorcinarene (RC8) carrier were prepared characterized. Microstructure surface of PIMs characterized by scanning electron microscope, FTIR, UV/vis spectroscopy, Thermogravimetric Analysis, respectively. In order to obtain information on the composition interactions that ma...

Promoter methylation is one of the main epigenetic mechanisms that lead to the inactivation of tumor suppressor genes during carcinogenesis. Due to the reversible nature of DNA methylation, many studies have been performed to correct theses epigenetic defects by inhibiting DNA methyltransferases (DNMTs). In this case novel therapeutics especially siRNA oligonucleotides have been used to specifi...