Dr Lavernia is from the Orthopaedic Institute at Mercy Hospital, Miami, Florida. Dr Lavernia is a designer for Zimmer and receives royalties on the CR Flex and the ML taper products. In this issue of Orthopedics, Dr Carlos Lavernia, medical director of the Orthopaedic Institute at Mercy Hospital, discusses research stating that female patients postpone necessary knee arthroplasty procedures mor...

We consider irreducible actions of locally compact product groups, and of higher rank semi-simple Lie groups. Using the intermediate factor theorems of Bader-Shalom and NevoZimmer, we show that the action stabilizers, and all irreducible invariant random subgroups, are co-amenable in some normal subgroup. As a consequence, we derive rigidity results on irreducible actions that generalize and st...

In this paper, according to G-Brownian motion and other related concepts properties, we define multiple Itô integrals driven by G-Lévy process. By using the G-Itô formula properties of G-expectation, two main theorems about integral are obtained proved. These provide powerful help for subsequent research on jump

Abstract. We investigate the impact of so-called energetic particle precipitation (EPP) indirect effect on lower stratospheric ozone, ClO, and ClONO2 in Antarctic springtime. use observations from Microwave Limb Sounder (MLS) Ozone Monitoring Instrument (OMI) Aura, Atmospheric Chemistry Experiment – Fourier Transform Spectrometer (ACE-FTS) SCISAT, Michelson Interferometer for Passive Sounding (...

This research aims to make a parallel and determine the symmetry between main male characters of Shakespearian play “The tragedy Hamlet, Prince Denmark”. For this purpose, each important character is analysed in-depth with use primary text other critical views. The approach used in paper was based on source, by employment quotes lines, verses how they manage be interpreted regarding portrayal c...

Abstract. In this study we report the synthesis of single crystals burbankite, Na3Ca2La(CO3)5, at 5 GPa and 1073 K. The structural evolution, bulk modulus thermal expansion burbankite were studied determined by two separate high-pressure (0–7.07(5) GPa) high-temperature (298–746 K) in situ single-crystal X-ray diffraction experiments. refined parameters a second-order Birch–Murnaghan equation s...

Introduction & Aims
 TKA in more active and young patients has prompted the interest durable biological methods of Osteo-integration with cementless components. With emergence improved biomaterials like porous titanium success, search for a long-term durability survivorship may have ended. This is retrospective study 492 consecutive TKAs using Cementless tibial fixation, reporting on e...

The 3',5'-cAMP-adenosine pathway (3',5'-cAMP→5'-AMP→adenosine) and the 2',3'-cAMP-adenosine pathway (2',3'-cAMP→2'-AMP/3'-AMP→adenosine) are active in the brain. Oligodendrocytes participate in the brain 2',3'-cAMP-adenosine pathway via their robust expression of 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase; converts 2',3'-cAMP to 2'-AMP). Because Schwann cells also express CNPase, it i...

AMP-activated protein kinase (AMPK) acts as a cellular energy sensor: it responds to an increase in AMP concentration ([AMP]) or the AMP-to-ATP ratio (AMP/ATP). Metformin and phenformin, which are biguanides, have been reported to increase AMPK activity without increasing AMP/ATP. This study tests the hypothesis that these biguanides increase AMPK activity in the heart by increasing cytosolic [...

The photoaffinity analog 2-azido-AMP was found to be a potent allosteric inhibitor of pig kidney fructose 1,6-bisphosphatase. UV-induced covalent incorporation of 2-azido-[8-3H]AMP fully inactivated the enzyme at a level stoichiometric with its subunit composition (4 mol of analog/mol of tetramer). The photoincorporation and inactivation were prevented by the presence of AMP but not by the subs...