نتایج جستجو برای: amodiaquine
تعداد نتایج: 753 فیلتر نتایج به سال:
Amodiaquine (AQ) is an antimalarial which is effective against chloroquino-resistant strains of Plasmodium falciparum but whose clinical use is severely restricted because of associated hepatotoxicity and agranulocytosis. "One-pot" synthesis of formamidines likely to be transformed into AQ derivatives is reported. Compared with AQ, the new compounds were devoid of in vitro cytotoxicity upon hum...
. Chloroquine resistance of Plasimdiam falciparum ( O F ) was first observed in Cameroon in 1985, in the south-west of the country, a region which is hyperendemic for malaria (Sansonetti et al., 1985). Although such resistance has since spread rapidly throughout the country (Louis et al., 1992; Basco et al., 1993), chloroquine still remains the most widely used antimalarial drug. Most of the in...
Conventional anti–malarial drugs (chloroquine, Artesunate, Quinine, Amodiaquine etc) are used by most malaria-endemic countries as first-line treatment for uncomplicated malaria. However, resistance plasmodium parasite against these conventional has necessitated the need herbal medicine alternative. So in this study, we formulate a mathematical model of malaria transmission two interacting popu...
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