the use of methanesulfonic acid as a brønsted acid for direct ortho-acylation of phenols and naphthols proves to be a convenient, more general and direct route to various hydroxyaryl ketones. the route is regioselective, leading to ortho c-acylated products in satisfactory to high yields in most cases. the solvent free reactions described below exhibited environmentally benign in terms of faste...

Rearrangement reactions of cycloalkenyl phenol and naphthyl ethers and the acid-catalyzed cyclization of the resulting product were investigated. Claisen rearrangement afforded 2-substituted phenol and naphthol derivatives. Combined Claisen and Cope rearrangement resulted in the formation of 4-substituted phenol and naphthol derivatives. In the case of cycloocthylphenyl ether the consecutive Cl...

By A. Jefferis Turner, m.d. (Intercolonial Medical Journal of Australasia.)?After describing the spread of anchylostomiasis in Australia, Dr. Turner gives his experience of treatment. He had disappointing results with calomel, santonin, male fern, naphthalin, naphthol, thymol, and other drugs. Ordinary doses of thymol, such as five grains thrice daily, he had found utterly useless; but on readi...

Most of the methods described for the determination of acetoin and biacetyl are based on the original Lemoigne-van Niel procedure (1, 2), which depends upon the formation of insoluble nickel dimethylglyoxime when biacetyl is treated with hydroxylamine in the presence of a nickel salt; acetoin is similarly determined after oxidation to biacetyl by heating with ferric chloride. In a recent modifi...

A procedureis presentedfor the automated determination of acid phosphatase activity in biological materials from either plant or animal origin. The Technicon N-i flow diagram has been simplified, and the reagents for the measurement of enzymatically produced phenolic substanceshave been modified without lossof range or sensitivity. Both phenyiphosphateand a-naphthylphosphate, introduced by Babs...