نتایج جستجو برای: amelanotic
تعداد نتایج: 594 فیلتر نتایج به سال:
Advanced melanoma is the most aggressive form of skin cancer. It is highly metastatic and dysfunctional in melanogenesis; two processes that are induced by H2O2. This work presents a melanoma cell model with low levels of H2O2 induced by catalase overexpression to study differentiation/dedifferentiation processes. Three clones (A7, C10 and G10) of human A375 amelanotic melanoma cells with quite...
Subungual melanoma is uncommon and accounts for just 2% to 3% of all cutaneous melanomas. Less than 10% of subungual melanomas are amelanotic and 90% of these occur on the thumb or great toe. They typically appear in the seventh decade of life and are associated with a delayed diagnosis and a poor prognosis. Amelanotic subungual melanoma generally manifests as a persistent vascular or ulcerated...
Cemiplimab is the first PD-1 inhibitor approved in United States for treatment of metastatic or locally advanced cutaneous squamous cell carcinoma (SCC) and basal (BCC), but not melanoma. We describe a case amelanotic melanoma (AM) developing patient on cemiplimab therapy invasive SCC. Cutaneous AM rare subtype that shows little no melanin pigmentation clinical histological examination thus oft...
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