Rat lungs were inflated and incubated in either anionic or cationic ferritin, and alveolar and capillary basement membranes were examined by electron microscopy. Cationic ferritin bound to heparan sulfate proteoglycans on the external surface of the alveolar basement membrane, whereas cationic ferritin bound to the lamina densa of the capillary basement membranes. Anionic and cationic ferritin ...

INTRODUÇÃO: A Proteinose Alveolar Pulmonar (PAP) é uma síndrome rara causada pelo acúmulo de surfactante no espaço alveolar, mais comumente encontrada em homens com idade média 20 a 50 anos. É patologia apresentação clínica variável e difícil diagnóstico, que pode cursar dispneia, tosse dor torácica. APRESENTAÇÃO DO CASO: RSM, sexo masculino, 39 anos, ex-tabagista um maço por dia, durante 8 que...

Moment-to-moment variation of effective alveolar Poi (Рлеоз) during the respiratory cycle was calculated based on a two-alveolar lung model in dogs anesthetized and pump-ventilated under various conditions induced by continuous infusion of sympathomimetics. Under fixed ventilation the amplitude of respiratory fluctuation of ΡΑ6ΟΙ(Δ Рлеог) increased with огСД Рлеог = 0.774· Voi + 1.862; p<0.001)...

Geiser, Thomas, Pierre-Henri Jarreau, Kamran Atabai, and Michael A. Matthay. Interleukin-1b augments in vitro alveolar epithelial repair. Am J Physiol Lung Cell Mol Physiol 279: L1184–L1190, 2000.—Biologically active interleukin (IL)-1b is present in the pulmonary edema fluid obtained from patients with acute lung injury and has been implicated as an important early mediator of nonpulmonary epi...

To facilitate study of alveolar macrophages in vivo, we developed a method to rapidly and efficiently replace resident alveolar macrophages with macrophages of a different (donor) genotype. Chimeric mice were generated by lethal irradiation followed by fetal liver transplantation (FLT) using green fluorescent protein (GFP) transgenic reporter mice as donors. Kinetics of peripheral blood monocyt...

Alveolar bone supports teeth during chewing through a ligamentous interface with tooth roots. Although tooth loads are presumed to direct the development and adaptation of these tissues, strain distribution in the alveolar bone at different stages of tooth eruption and periodontal development is unknown. This study investigates the biomechanical effects of tooth loading on developing alveolar b...