Propolis, also known as bee glue, is a substance collected by worker bees and it is used as a material for constructing and maintaining their beehives. It has been used topically and orally by humans for its anti-inflammatory properties. However, the growing use of propolis has been paralleled by reports of allergic contact dermatitis as a reaction to the substance. Contact dermatitis with gene...

Allergic contact dermatitis is a T cell mediated, antigen-specific inflammatory reaction of the skin due to repeated epicutaneous exposure to antigens. Immunologically it is divided into 2 phases, induction and elicitation phase. During the first phase which is clinically silent, naïve T cells are activated and differentiate into antigen-specific memory T cells. During the elicitation phase, af...

Formaldehyde is a colorless gas with a pungent odor that is widely used as a preservative in toiletries and cosmetics and in products for household and industrial use. Both formaldehyde itself and substances that can release it are a common cause of allergic contact dermatitis. This condition often becomes chronic, given that these allergens are found nearly everywhere and it is difficult for p...

Thrombocid® ointment (Lacer, Barcelona, Spain) is widely used in Spain and other countries for varicose veins and 22 hematomas. To our knowledge, there are no reported cases of allergic contact dermatitis following its use. Herein we present 23 two cases of allergic contact dermatitis to Thrombocid® ointment, owing to cetearyl alcohol.

Allergic contact dermatitis related to para-phenylendiamine (PPD) from temporary black henna tattoos and hair dyes has become an epidemic in recent years. Several cases of adverse skin reactions to PPD have been reported in the literature. Herein, we present a case of angioedema-like allergic contact dermatitis related to hair coloring with henna.

Local anesthetics are widely used in clinical practice, and adverse effects are not uncommon. Delayed hypersensitivity reactions are among the most common effects, but immediate-type reactions may also occur. Patch testing should be considered in patients with hypersensitivity reactions. We present a case of allergic contact dermatitis to benzocaine that was detected incidentally by patch testi...

BACKGROUND Hand eczema is not uncommon in children but it is rarely studied using skin-prick tests. Few reports have addressed their usefulness in children and none has specifically analyzed their use in children with hand eczema. MATERIAL AND METHODS We performed a retrospective study of all children up to 16years of age with hand eczema who were assessed in the Department of Dermatology at ...

Diethyl sebacate is used in topical medicaments in United States and Japan. We described a case of allergic contact dermatitis from diethyl sebacate in a topical antimycotic medicament. Allergic reaction to diethyl sebacate is likely more common because our group has found three of eight sensitized cases. We believe that an investigation regarding the sensitized frequency to diethyl sebacate wo...

Allergic contact dermatitis caused by phenylethyl resorcinol [4-(1-phenylethyl)-1,3-benzenediol], a skin-lightening agent in cosmetics Michi Gohara1,2, Akiko Yagami1, Kayoko Suzuki3, Yusuke Morita1, Akiyo Sano1, Yohei Iwata1, Takashi Hashimoto2 and Kayoko Matsunaga1 1Department of Dermatology, Fujita Health University School of Medicine, Aichi, 470-1192, Japan, 2Department of Dermatology, Kurum...

Irritant or allergic contact dermatitis usually presents as an eczematous process, clinically characterized by erythematoedematovesicous lesions with intense itching in the acute phase. Such manifestations become erythematous-scaly as the condition progresses to the subacute phase and papular-hyperkeratotic in the chronic phase. Not infrequently, however, contact dermatitis presents with nonecz...