نتایج جستجو برای: all disease

تعداد نتایج: 3090296  

پایان نامه :دانشگاه آزاد اسلامی واحد علوم پزشکی تهران - دانشکده پزشکی 1389

هدف: این مطالعه به مقایسه میزان اثربخشی دو روش متداول درمان بیماری all دوران کودکی در مرکز طبی کودکان انجام شده است. روش مطالعه: این مطالعه به صورت یک بررسی مشاهده ای (observational) از نوع طولی (longitudinal) و به صورت کوهورت گذشته نگر (historical cohort) انجام شده است. حجم نمونه مورد بررسی شامل 246 کودکی بود که طی سالهای 1370 تا 1386 در مرکز طبی کودکان با تشخیص all بستری شده و تحت درمان قرار...

2012
Anthony J. Apostoli Christopher J. B. Nicol

ATP-dependent binding cassette (ABC) transporters are a family of transmembrane proteins that pump a variety of hydrophobic compounds across cellular and subcellular barriers and are implicated in human diseases such as cancer and atherosclerosis. Inhibition of ABC transporter activity showed promise in early preclinical studies; however, the outcomes in clinical trials with these agents have n...

2011
William Ryan Spiker Alpesh A Patel

Back pain is the second most common reason for patients to seek medical care in the USA [1]. Low back pain is estimated to occur in up to 84% of individuals at some point in their life, and lumbar disc degeneration is one of the most common findings in the work-up of low back pain [2]. Owing to its prevalence, it is not surprising that the diagnosis and treatment of low back pain has a large so...

2012
Tara M. Weitz Terrence Town

Neuroinflammation is now regarded as both an early event and prime mover in the pathobiology of Alzheimer disease (AD), a neurodegenerative disease that represents a growing public health threat. As the resident innate immune cells within the central nervous system, microglia are centrally positioned as key orchestrators of brain inflammation. It is now accepted that numerous forms of activated...

2013
Youn-Sig Kwak David M. Weller

In agro-ecosystems worldwide, some of the most important and devastating diseases are caused by soil-borne necrotrophic fungal pathogens, against which crop plants generally lack genetic resistance. However, plants have evolved approaches to protect themselves against pathogens by stimulating and supporting specific groups of beneficial microorganisms that have the ability to protect either by ...

Journal: :Neurology India 2007
Roshan Lal Koul

Three siblings (two girls and one boy) and their father are reported who developed Huntington's disease (HD). The two girls had onset at less than six years of age, while the boy started with symptoms at 12 years of age. The girl, the child number two, has expired and the youngest one is in a vegetative state. The elder brother is still mildly affected. The disease presented in a severe form an...

Journal: :Medical hypotheses 2004
L Broxmeyer

By the turn of the last century, flying in the face of over a hundred years of research and clinical observation to the contrary, medicine abandoned the link between infection and atherogenesis; not because it was ever proven wrong, but because it did not fit in with the trends of a medical establishment convinced that chronic disease such as heart disease must be multifactorial, degenerative a...

2016
Umberto Volta Maria Gloria Mumolo Giacomo Caio Elisa Boschetti Rocco Latorre Fiorella Giancola Paola Paterini Roberto De Giorgio

A 62-year-old woman complaining of severe malabsorption was diagnosed with celiac disease based on the findings of flat, small intestinal mucosa and HLA-DQ2 positivity, although celiac serology was negative. This diagnosis was questioned due to the lack of clinical and histological improvement after a long period of strict gluten-free diet. The detection of enterocyte autoantibodies guided to t...

Journal: :Postgraduate medical journal 2006
C J R Goddard H R Gillett

Coeliac disease is a common condition that is increasingly being recognised as a result of the development of sensitive and specific serology. The diagnosis of coeliac disease and its subsequent treatment with a gluten-free diet have implications for the patient, not just for symptom control but also for the possible effect on quality of life and risk of complications. Whether the mode of prese...

2012
Sanjay Sinha

The emerging field of stem cell medicine offers unprecedented opportunities, among which the ability to model genetic diseases in vitro is one of the most exciting. In particular, disease modeling using stem cells promises to deliver a deeper understanding of disease mechanisms and to provide a test bed for novel therapies within a relatively short timeframe. The seminal discovery by Shinya Yam...

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