Mason A. Porter∗1, Martin Centurion2, Ye Pu3, P. G. Kevrekidis4, D. J. Frantzeskakis5, and Demetri Psaltis3 1 Mathematical Institute, University of Oxford, OX1 3LB, United Kingdom 2 Max Planck Institute for Quantum Optics, 85748 Garching, Germany 3 Department of Electrical Engineering, California Institute of Technology, Pasadena, CA 91125, USA 4 Department of Mathematics and Statistics, Univer...

Michael Gronau, 2 Dan Pirjol, Amarjit Soni, and Jure Zupan 6 Physics Department, Technion–Israel Institute of Technology 32000 Haifa, Israel Stanford Linear Accelerator Center, Stanford University, Stanford, CA 94309 Center for Theoretical Physics, Massachusetts Institute for Technology, Cambridge, MA 02139 Physics Department, Brookhaven National Laboratory, Upton, New York 11973 5 Department o...

1 Molina Center for the Energy and the Environment (MCE2), La Jolla, CA, USA 2 Department of Earth, Atmospheric and Planetary Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA 3 Centro Nacional de Investigación y Capacitación Ambiental del Instituto Nacional de Ecologı́a (CENICA-INE), D.F., México 4 Japanese International Cooperation Agency (JICA), Tokyo, Japan 5 Atmospheric En...

1 Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Kweishan 333, Taiwan 2Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA 3HELIOS ENDO-Klinik Hamburg, Holstenstraße 2, Hamburg 22767, Germany 4Department of Orthopaedic Surgery, Stanford University Medical Center, Palo Alto, CA 94304, USA 5 Skeletal Diseases Ge...

Among the four protease-activated receptors (PARs), PAR-1 plays an important role in normal lung functioning and in the development of lung diseases, including fibrosis. We compared the expression and functional activity of PARs in normal and fibrotic human lung fibroblasts. Both normal and fibrotic cells express PAR-1, -2, and -3, with PAR-2 showing the lowest level. There was no significant d...

Meteoritic zircons are rare, but some are documented to occur in asteroidal meteorites, including those of the howardite–eucrite–diogenite (HED) achondrite clan (Rubin, A. [1997]. Meteorit. Planet. Sci. 32, 231– 247). The HEDs are widely considered to originate from the Asteroid 4 Vesta. Vesta and the other large main belt asteroids record an early bombardment history. To explore this record, w...

Rhynchophylline (Rhy) is an active component isolated from species of the genus Uncaria which has been used for the treatment of ailments to the central nervous system in traditional Chinese medicine. Besides acting as a calcium channel blocker, Rhy was also reported to be able to protect against glutamate-induced neuronal death. We thus hypothesize that Rhy may have neuroprotective activity ag...

OBJECTIVES To compare hypertension-related mortality (HRM) age-standardized and age-specific rates for Hispanic subgroup and non-Hispanic White (NHW) women; to identify underlying causes of HRM by Hispanic subgroup and age; and to examine relative percent change in HRM among Hispanic subgroups and NHW women. DESIGN Secondary data analyses of 1995-1996 and 2001-2002 national vital statistics m...

Life began very early in Earth's history, perhaps before 3800 million years ago (Ma) (1), and achieved remarkable levels of metabolic sophistication before the end of the Archean around 2500 Ma (2, 3). The great antiquity of our biosphere might indeed illustrate how easily life can arise on a habitable planet, but it also portends the challenges that confront our efforts to become intimately fa...

We applied multiple geochemical tracers (87Sr/86Sr, [Sr], d13C, and d18O) to waters and carbonates of the lower Colorado River system to evaluate its paleohydrology over the past 12 Ma. Modern springs in Grand Canyon reflect mixing of deeply derived (endogenic) fluids with meteoric (epigenic) recharge. Travertine (<1 Ma) and speleothems (2–4 Ma) yield 87Sr/86Sr and d13C and d18O values that ove...