Using saturated alkyl chain series with a dithiol anchor group, we systematically examined the intrinsic charge transport of single-molecule junctions in an electromigrated nanogap electrode. The saturated alkyl molecular system constitutes an important control series in molecular transport experiments to corroborate valid molecular junctions, because molecular energy levels remain nearly uncha...

A novel alkyl iodide bearing an azlactone group was successfully employed as a reversible complex-mediated polymerization (RCMP) initiator for synthesizing the first-time well-defined α-azlactone-terminated polymethacrylates ( Đ < 1.30). The amine-scavenging ability of resulting functional polymers demonstrated by using benzylamine.

Alkyl gallates are anticipated for their use as anti-bacterial and anti-viral agents. Although their pharmacological activities depend on their alkyl chain length, no mechanism has yet been clarified. As described herein, we investigated the membrane binding properties of a series of alkyl gallates using fluorescence measurement to elucidate their different pharmacological activities. Membrane ...

A photoredox-mediated Minisci C–H alkylation reaction of N-heteroarenes with alkyl boronic acids is reported. A broad range of primary and secondary alkyl groups can be efficiently incorporated into various N-heteroarenes using [Ru(bpy)3]Cl2 as photocatalyst and acetoxybenziodoxole as oxidant under mild conditions. The reaction exhibits excellent substrate scope and functional group tolerance, ...

The chemisorption of 1-octanethiol [CH3(CH2)6CH2SH] from the vapor phase on the GaN(0001)-(1 × 1) surface has been studied using X-ray photoemission, ultraviolet photoemission, and X-ray-excited Auger electron spectroscopies. Quantitative analysis of relative peak intensities indicates that the molecule adsorbs via the thiol group with a saturation coverage of ∼0.28 monolayers and with the alky...

When an alkyl halide is prepared from an alcohol and a hydrogen halide, protonation converts the LOH group into a good leaving group. However, if the alcohol molecule contains a group that might be sensitive to strongly acidic conditions, or if milder or even nonacidic conditions must be used for other reasons, different ways of converting the LOH group into a good leaving group are required. M...

Haptens with bridge at the 2-position have not yet been explored. Radioimmunoassays with antibodies directed against 2 alpha-alkyl bridged steroid haptens are expected to be highly specific due to greater topographical exposure and similarity in conformation to the native steroid. The 2 alpha-alkyl bridged haptens were synthesized by first adding a cyclopropane ring to 2-methylene-4-en-3-one. S...

Some alkyl and aryl derivatives of 9H-purine-6-thiol were synthesized and evaluated in vitro and in vivo for potential antithyroid effects. Spectrophotometric studies demonstrated 1:1 charge transfer complexation between iodine and these compounds with quite high values of the formation constants. The blood assays of rats treated with these compounds revealed significant antithyroid activity fo...

The basic retention mechanisms of reversed-phase and hydrophilic-interaction liquid chromatography (HILIC) were quantitatively analyzed using simple molecular mechanics (MM) calculations. The model bonded phases were composed of an alkyl chain bonded to siloxane-like molecules. The head of the alkyl chain was a hydroxyl group, used to study retention mechanisms of HILIC. The standard analytes w...

background: alkyl hydroperoxide reductase (ahpc) of helicobacter pylori is considered as a diagnostic antigen. there­fore, this antigen can be used to detect h. pylori infection by stool immunoassays such as elisa. the aim of this study was to simplify the ahpc protein purification procedures. methods: for whole cell protein extraction, the bacterial cells were ruptured by octly-β-d glucopyrano...