ALG-2 (gene name: PDCD6) is a penta-EF-hand Ca(2+)-binding protein and interacts with a variety of proteins in a Ca(2+)-dependent fashion. ALG-2 recognizes different types of identified motifs in Pro-rich regions by using different hydrophobic pockets, but other unknown modes of binding are also used for non-Pro-rich proteins. Most ALG-2-interacting proteins associate directly or indirectly wit...

Antilymphocyte and antithymocyte globulins (ALG) are currently used as immunosuppressive agents in clinical transplantation and for the treatment of severe aplastic anemia. ALG contain a mixture of antibodies that recognize Tand B-cell-specific antigens but mostly nonlineage-specific molecules. We reported previously that ALG could inhibit the proliferation of activated B cells and B cell lines...

Wound infection hinders adequate healing, being particularly grievous and prevalent in burn wounds chronic wounds. extends inflammation, preventing epithelialization angiogenesis. Therefore, prolongs healing time, steeply increases treatment costs degrades patients wellbeing. One successful strategy to control wound is apply an active dressing, able eliminate or significantly reduce the microbi...

A general algorithm, called ALG, for online and semi-online scheduling problem Pm||Cmax with m ≥ 2 is introduced. For the semi-online version, it is supposed that all job have their processing times within the interval [p, rp], where p > 0, 1 < r ≤ m/m− 1. ALG is a generalization of LS and is optimal in the sense that there is not an algorithm with smaller competitive ratio than that of ALG.

Status of this Memo This memo provides information for the Internet community. It does not specify an Internet standard of any kind. Distribution of this memo is unlimited. This document describes an SNMP application layer gateway (ALG), which may be useful in certain environments. The document does also list the issues and problems that can arise when used as a generic SNMP ALG. Specifically, ...

 Abstract Background: Lymphoproliferative disorders are among the most serious and potentially fatal complications of chronic immunosuppression in kidney transplant recipients. The principle risk factors for development of PTLD are the degree of overall immunosuppression and the EBV serostatus of the recipient. In this study, the risk of PTLD in kidney transplant recipients who received Anti- L...

Single nucleotide polymorphisms (SNPs) are the most commonly used polymorphic markers in genetics studies. Among the different platforms for SNP genotyping, Luminex is one of the less exploited mainly due to the lack of a robust (semi-automated and replicable) freely available genotype calling software. Here we describe a clustering algorithm that provides automated SNP calls for Luminex genoty...

Antilymphocyte globulin (ALG) was given every other day for 5 doses with platelet transfusions immediately following ALG administration in 6 patients with aplastic anaemia. Four patients responded and 3 durable remissions were achieved. One patient relapsed and further treatment with anti-thymocyte globulin and cyclosporin also failed. One patient died of Flavobacterium septicaemia 6 days after...

The perovskite nanopowders of lanthanum strontium cobalt ferrite (LSCF) have been synthesized using the alginate mediated ion-exchange process. This perovskite-based material is a promising cathode for intermediate-temperature solid oxide fuel cells (IT-SOFCs) due to its high electrical conductivity, low polarizability, catalytic activity oxygen reduction, enhanced chemical stability at an elev...

BACKGROUND Basiliximab is a chimeric human/mouse monoclonal antibody directed against the alpha chain of the IL-2 receptor, CD25, which has been reported as successfully reducing rejection in adult renal transplant recipients. Reported clinical experience of basiliximab in paediatric renal transplantation is limited. METHODS Using two intravenous doses on day 0 (pre-operatively) and day 4 wit...