Marchiafava-Bignami disease is a rare toxic encephalopathy seen mostly in chronic alcoholics due to progressive demyelination and necrosis of the corpus callosum. It may involve adjacent white matter and subcortical regions. We present here the magnetic resonance imaging findings of Machiafava-Bignami disease in a chronic alcoholic patient. In 1903, Italian pathologists Marchiafava and Bignami ...

Over a 1-year study period all patients admitted to the department of psychiatry in a general hospital were asked to complete the General Health Questionnaire at admission, discharge, and first polyclinic (outpatient) follow-up contact. Seventeen per cent of admissions were alcoholics. Alcoholics improved rapidly after admission to the psychiatric department. This improvement was comparable to ...

Multifocal avascular osteonecrosis is an uncommon entity having a predominant association with steroids and less commonly with alcohol abuse. In literature only few cases of alcohol induced multifocal avascular osteonecrosis involving both hips and shoulder are reported. To the best of our understanding this is the first case report or contribution from nuclear medicine court and it would help ...

BACKGROUND/AIM The aim of this study was to investigate the state of chromatin condensation in peripheral blood leukocytes of alcoholics, during the early detoxification period, in order to highlight structural modifications, indicating epigenetic mechanisms regulated by alcohol. MATERIALS AND METHODS Blood samples were obtained from alcoholic patients, who were admitted for detoxification on...