T FIAT VITAMIN B12 IN SERUM is l)ound to protein14 has been known since shortly after the isolation of the vitamin. Endogenous vitamin B12 (which may be mainly methyl-Bi2) is bound primarily to an a1-globulin 2.6-10 hut vitamin B12 added to serum in vitro hinds primarily to -globuun (presumably because B12-binding a-globulin is normally almost saturated with endogenous vitamin B12).61#{176} hal...

Quantification of the permeability of connective tissue linings isolated from implanted capsules was achieved by two types of experiments. The objective of the first type was to determine the restriction offered by the lining to diffusion of 125I-labeled human serum albumin. The restricted diffusion coefficient of albumin with respect to the connective tissue lining the luminal capsule surface ...

The long-standing observations that respiratory secretions contain virus-neutralizing substances (1-3) have recently been extended by the demonstration that antibody activity associated with the yA-globulin in nasal secretion may protect against respiratory virus infection (4). Since protection was most clearly seen in individuals with relatively high titers of nasal antibody, and since yA-glob...

Diffuse glomerulonephritis was induced in unilaterally nephrectomized albino rabbits by giving them two massive intravenous injections of purified bovine serum gamma globulin. Morphologically, these renal lesions were similar to those of human acute and subacute glomenilonephritis. Globulin nephritis in rabbits also closely resembles experimental nephritis induced by injection of other foreign ...

The globulin content of the standard solution in the vials is standardized either by a Kjeldahl or a biuret determination. When available Lederle (gamma) globulin diluted 1:200 can be used for this purpose as well. The diluted Lederle standard globulin coagulates on heating and so cannot be used as a sterilized standard. An interesting phenomenon was observed while preparing the sterilized wate...

Liver is a vital organ in the body that perform very important functions to keep health hemostasis. function tests are group of determine liver physiological and pathological conditions. The main objectives present study were assess using panel among sample patients compare their levels with subjects who had no disease. To achieve objectives, we analyzed dataset posted on Kaggle. described Indi...

Liver is a vital organ in the body and works to filter blood from digestive tract before passing it on rest of body. diseases are varied may be assessed by liver function tests including ALT. The main objectives this study were use neural network analysis predict disease, identify relative contribution disease predictors. A dataset Indian patients posted Kaggle was used analyzed for prediction....

Calculated globulin (total protein - albumin) is usually tested as part of a liver function test profile in both primary and secondary care and determines the serum globulin concentration, of which immunoglobulins are a major component. The main use hitherto of calculated globulin is to detect paraproteins when the level is high. This study investigated the potential to use low levels of calcul...