Background: Epilepsy is one of the most prevalent non-communicable neurologic diseases leading to significant disability and mortality. Complaints of impaired learning and memory are common in patients of epilepsy. Antiepileptic drugs (AEDs) may further enhance this impairment. So the present study was carried out on albino rats to evaluate the effect of AEDs on learning and memory. Objective: ...

INTRODUCTION This study investigated the curcumin effect on the cerebral aneurysm. Apoptosis is known to play a fundamental role in the pathogenesis of a cerebral aneurysm. Therefore, we investigated the effect of curcumin on apoptosis of smooth muscle cells of a cerebral aneurysm-induced male albino rats. METHODS In this study, the cerebral aneurysm has been induced in the male albino rats b...

depression is a heterogenous, multifaceted disorder with symptoms manifested at the psychological, behavioral and physiological level. therefore, present study was designed as a model to analyze the long lasting effects of methylmercury chloride in male rats with a focus on depression like behavior. male albino rats of wistar strain were exposed orally to a dose of 2 mg/kg of methylmercury chlo...

Bone fracture healing is a complex process involving multiple mechanisms where immune system has vital role. The spleen part of this and its effect on bone metabolism not completely understood. Herein, the effects simultaneous fractures splenectomy were evaluated regarding early late periods in rats. closed model was applied sixty-four healthy male Wistar-albino Rats randomly selected divided i...

Objective: To evaluate the restoration of sperm motility with antioxidant oils (Virgin coconut oil and Corn oil) therapy in Phenytoin induced testicular toxicity rats. Study Design: Experimental Study. Setting: Al-Tibri Medical College Hospital. Period: November 2019 to March 2020. Material & Methods: Forty-eight male albino rats weighing between 150-250gms were taken from animal house medi...

Ganoderma lucidum (GL) is a widely used medicinal mushroom. The therapeutic effect of this fungus on many diseases has been proven by studies. aim study to assess the effects low, moderate and high dose GL extract administration testis tissue, spermatogenic series cells sperm motility in rats. 40 Wistar albino rats were randomly divided into 4 groups. Rats group 1, 2, 3 administered 2 ml physio...

Background: Peptic ulcer has become an immense problem in our health care system. One of the major cause being overuse NSAIDs Pakistan.
 Objective: To evaluate gastro protection by Vitamin E, C and combination E on morphology aspirin induced gastric mucosal injury albino rats.
 Methodology: 45 adult rats were taken organized into 5 groups. Control was formed Group I. II given aspirin....

The increasing use of plant-based medicines necessitates safety evaluations all medicinal plants. This study evaluated the effects mango (Mangifera indica) leaf extracts on albino rats (Rattus norvegicus). phytochemistry plant’s extract was evaluated, followed by a determination its acute toxicity using 24 rats. Thereafter, chronic determined another set rats, separated into four groups six eac...

Compensatory hypertrophy of the kidney in albino rats becomes less as age advances. There is a rapid decrease from 5 days to 60 days of age and then a slow diminution throughout adult life.

Aims: This research investigated the curative effects of Moringa oleifera (MO), Treculia africana (T.A.), and Albizzia chevalieri (A.C.) plant extracts on liver function indices in Alloxan-induced diabetic rats.
 Study Design: Albino rats were grouped into five (5) main groups MO, TA, A.C., Normal Control (N.C.), Diabetic (D.C.) groups.
 Place Duration Study: Department Science Labora...