The zona limitans intrathalamica (ZLI) is located at the border between the prospective ventral thalamus and dorsal thalamus, and functions as a diencephalic signaling center. Little is known about the mechanism controlling ZLI formation. Using a combination of fate-mapping studies and in vitro assays, I show that the differentiation of the ZLI from progenitor cells in the alar plate is initiat...

Objective: To compare anatomy of sacral hiatus between the genders case and control groups. determine significance hiatal variations cases controls. Study Design: Case-control study. Setting: PNS Shifa Hospital Karachi. Period: January 2020 to June 2020. Material & Methods: Total 178 participants aged 18-65 years were enrolled in Approval was taken from Ethical Review Committee Bahria Unive...

OBJECTIVE The aim of the present study was to use facial analysis to determine the effects of rapid maxillary expansion (RME) on nasal morphology in children in the stages of primary and mixed dentition, with posterior cross-bite. MATERIAL AND METHODS Facial photographs (front view and profile) of 60 patients in the pre-expansion period, immediate post-expansion period and one year following ...

We tested the possibility of inducing ectopic expression of the gene Engrailed-2 (En-2) in the rhombomeres of the 2-days-old chick embryo. The experimental procedure consisted of grafting En-2-expressing neuroepithelium (prospective isthmocerebellum) from a quail or a mouse embryo into different rostrocaudal levels in the hindbrain of a host chick embryo. The graft replaced a given excised host...

INTRODUCTION The size, angle, shape and type of nose are a signature indicating race, age and sex. OBJECTIVE Describe and compare nasal angles, nose types, nostril models, and nasal profiles in young Turkish males and females. METHODS The study group consisted of university students, 56 males and 59 females. Nasal measurements were obtained from all subjects, using anthropometric methods. ...

Nasolabial cyst is a rare nonodontogenic, soft-tissue cyst occurring in the sublabial area and anteriormaxillary region. The nasolabial cyst is classified as a fissural cyst, found outside the bone, and on the region corresponding to the nasolabial furrow and alar nose. This cyst is frequently asymptomatic with the most usual sign being alar nose elevation. In spite of the low occurrence of nas...

Since the nose is located in the center of the face, small asymmetries and imperfections are easily recognized. One subunit of the nose is the nasal ala, a region that, when reconstructed, requires the achievement of esthetic and functional results. This poses a challenge to the plastic surgeon. In this article, we describe 3 cases of composite auricular grafts used for nasal alar reconstructio...

We present an uncommon case of nasal alar and facial necrosis following calcium hydroxylapatite filler injection performed elsewhere without direct physician supervision. The patient developed severe full-thickness necrosis of cheek and nasal alar skin 24 h after injections into the melolabial folds. Management prior to referral included oral antibiotics, prednisone taper, and referral to a der...