objective this is the first report of cns involvement by the new influenza virus (influenza a [h1n1]) in iran. the patient was a 10-year-old boy with chief complaints of fever, malaise, and cranial nerve involvement, resulting in respiratory muscle paralysis and intubation. this shows that the new influenza virus, as well as the seasonal flu, can cause neurologic complications; however, the sev...

conclusions this study showed that the prevalence rates of hav and hev antibodies were positively correlated with age. the results demonstrated that the infection with these two viruses in the region was high and some high-risk individuals including females at child-bearing age were more susceptible. hav vaccination could be recommended for antibody-negative adults. results the results showed t...

background: the present study sought to investigate molecular evidence for association between the presence of herpes simplex virus (hsv), cytomegalovirus (cmv), and epstein-barr virus (ebv) in crc and colorectal polyp by using the pcr method in iran. methods: in this analytical case-control study, we selected 15 patients with crc, 20 patients with colorectal polyp, and 35 patients without mali...

conclusions cd5l might be a useful biomarker for early diagnosis of hcc in hcv cirrhotic patients. lrg and hp α2 isoforms could be potential markers for distinguishing viral hcc. our results also further support the presence of varying molecules involved in hepatocarcinogenesis in hbv when compared with hcv infection. patients and methods two-dimensional polyacrylamide gel electrophoresis combi...

conclusions hbv and hcv are important culprits of hcc in emro countries and the middle east and different nations need different strategies to tackle them accordingly. countries with high rates of hbv such as turkey should continue their hbv vaccination and also increase sanitation. nations with high hcv rates such as egypt should maintain their blood product monitoring in addition to increased...

conclusions the diagnosis of the high frequency of solitary ttv and co-infection with hbv, in both liver transplanted patients with cryptogenic and determined cirrhosis, emphasized on the importance of ttv infection in the development of cirrhosis, especially in the cases of cryptogenic ones, prompting for further studies the confirm this agent in the etiology of determined cirrhosis. results t...

this experimental study was carried out to induce a co-infection of h9 aiv and ibv with inoculumsprepared from tracheal scrubbed epithelium tissues in natural co-infected birds to rule out the effect of fieldundesired environmental conditions and also other infectious causative agents. eighty 1-day-old broilerswere randomly divided into four equal groups. at 21 days of age, three test groups we...

the measurement of antibody responses of animals exposed to bvdv either through a natural exposure or an immunization protocol is still a standard procedure. for bvdv, the test formats have been largely limited to elisa which is a valuable diagnostic test to measure the level of bvdv specific antibodies as well as antigen in blood samples. in the present study, 120 blood samples were collected ...

infectious bronchitis (ib) and newcastle disease (nd) are highly contagious and the most economically important diseases of the poultry affecting respiratory tract and causing economic losses in poultry industry throughout the world. in the present study, the simultaneous detection and differentiation of causative agents of these diseases were investigated using duplex-rt-pcr. rna was extracted...

Background:In the recent decade, the reverse genetics method has been broadly used for rescue of negative-stranded RNA viruses from cDNA or viral minigenomes. This technique has been applied to study different steps in virus replication and virus-host interactions. Reverse genetics could also be implemented for design of new vaccines. The T7 RNA polymerase activity as well as virus (nucleocapsi...