نتایج جستجو برای: airway reactivity

تعداد نتایج: 138470  

2001
Joris Kloek Ingrid van Ark Gert Folkerts Nanne Bloksma Craig M. Lilly Fred De Clerck Jeffrey M. Drazen Frans P. Nijkamp

Substantial evidence suggests that oxidative stress in the lungs can affect the pathological events observed in asthma. We used a guinea pig model of asthma to assess whether the early asthmatic reaction is associated with decreased lung levels of glutathione, and whether a decrease in glutathione is implicated in the increased airway smooth muscle reactivity that is associated with exposure of...

Journal: :Environmental Health Perspectives 2002
David B Peden

Asthma is a disease characterized by intermittent bronchoconstriction due to increased airway reactivity to both allergic and nonallergic stimuli. Most asthma exacerbations that result in hospitalization are associated with viral upper respiratory tract infections. Such infections typically induce T-helper type 1 (T(H)1) responses in the airway, involving activation of nuclear factor-kappaB (NF...

Journal: :Thorax 2010
Carolina Cisneros Francisco García-Río Delia Romera Carlos Villasante Rosa Girón Julio Ancochea

BACKGROUND A very weak relationship has been reported between the health-related quality of life (HRQL) of patients with asthma and their degree of airway hyper-responsiveness (AHR), evaluated in terms of sensitivity. However, this relationship still has not been sufficiently explored for bronchial reactivity indices. OBJECTIVES To analyse the relationship between bronchial reactivity and sen...

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