The triad of bronchial asthma, nasal polyposis, and intolerance to aspirin and aspirin-like chemicals are designated aspirin-induced asthma (AIA) or Samter's syndrome. The exact mechanism of the disease is unknown but it is thought to be a disorder of arachidonic acid metabolism. These patients are frequently referred to allergy clinics for preoperative evaluation for possible anesthetic agent ...

Objective The aim was to study the therapeutic effects and mechanisms of QWRG on adjuvant-induced RA in rats. Methods The RA rat models were manipulated and subsequently divided into five experimental groups: AIA, DEX, and QWRG groups. The paw volume, body weight, arthritic score, and mechanical nociceptive threshold were assessed. The serum levels of the RF, MDA, ALP, AST, ALT, IL-1β, IL-2, ...

Pain is a dominant symptom of rheumatoid arthritis (RA) and its adequate treatment represents a major unmet need. However, the cellular mechanisms that drive arthritis pain are largely unexplored. Here, we examined the changes in the activity of joint sensory neurons and the associated ionic mechanisms using an animal model of antigen-induced arthritis (AIA). Methylated-bovine serum albumin (mB...

PURPOSE The reverse posterior interosseous artery flap has several advantages, not sacrificing any major blood vessel, but its relatively short pedicle limits the use to cover defects up to the metacarpophalangeal joint. Our purpose is to demonstrate that the ligature of the anterior interosseous artery (AIA), proximal to the communicating branch with the posterior interosseous artery, leads to...

A protective and anti-inflammatory role for CD1d-dependent NKT cells (NKTs) has been reported in experimental and human autoimmune diseases. However, their role in arthritis has been unclear, with conflicting reports of CD1d-dependent NKTs acting both as regulatory and disease-promoting cells in arthritis. These differing modes of action might be due to genetic differences of inbred mice and in...

A new design of dual-port monopole-slot-like microstrip active integrated antenna (AIA) is presented and discussed in this paper. The primary designed passive antenna is capable of supporting two different WLAN bands at 2.4–2.84 GHz and 5.15–5.35 GHz due to its dual-port structure. In order to reduce the transmission coefficient between the two ports of antenna a coupling sleeve-arm and an inve...

Cognitive abilities are largely dependent on activation of cerebral tropomyosin-related kinase B receptors (TrkB) by brain-derived neurotrophic factor (BDNF) that is secreted under a bioactive form by both neurons and endothelial cells. In addition, there is mounting evidence for a link between endothelial function and cognition even though the underlying mechanisms are not well known. Therefor...

This research note attempts to present Philippine-based archeological impact assessments (AIA) archeologists “how to” possibly approach spread-out or large-scale project sites through the integration of various aerial remote sensing platforms in work process. Cascading providing multiscalar (macro, meso, and micro) perspectives are presented conjunction with complimentary method stratified rand...

Decayless kink oscillations of an ensemble loops are captured simultaneously by the High Resolution Imager (HRI) Extreme Ultraviolet (EUI) and Atmospheric Imaging Assembly (AIA) from 22:58 UT on 5 November to 00:27 6 2021. Oscillations analysed processing image sequences taken two instruments with a motion magnification technique. The around 51 Mm in length, oscillate short periods 1-3 min (1.6...

We present observations of the occulted active region AR 12222 during the third Nuclear Spectroscopic Telescope ARray (NuSTAR) solar campaign on 2014 December 11, with concurrent Solar Dynamics Observatory (SDO)/ AIA and FOXSI-2 sounding rocket observations. The active region produced a medium-size solar flare 1 day before the observations, at ∼18 UT on 2014 December 10, with the post-flare loo...