نتایج جستجو برای: ags cell line

تعداد نتایج: 1970911  

Journal: :Blood 2012
Melinda A Biernacki Yu-tzu Tai Guang Lan Zhang Anselmo Alonso Wandi Zhang Rao Prabhala Li Zhang Nikhil Munshi Donna Neuberg Robert J Soiffer Jerome Ritz Edwin P Alyea Vladimir Brusic Kenneth C Anderson Catherine J Wu

Targets of curative donor-derived graft-versus-myeloma (GVM) responses after allogeneic hematopoietic stem cell transplantation (HSCT) remain poorly defined, partly because immunity against minor histocompatibility Ags (mHAgs) complicates the elucidation of multiple myeloma (MM)-specific targets. We hypothesized that syngeneic HSCT would facilitate the identification of GVM-associated Ags becau...

2013
JUN MA MIN SHI GUANGMING LI NA WANG JUE WEI TING WANG JIALI MA YUGANG WANG

We investigated the inhibition of apoptosis and proliferation of poorly differentiated AGS gastric cancer cells by epigallocatechin-3-gallate (EGCG), to establish target genes for regulation by EGCG. The proliferation and apoptosis of AGS gastric cancer cells treated with EGCG were observed by cell counting kit (CCK)-8 and flow cytometry. Differential gene expression in AGS cells treated with E...

Journal: :Journal of immunology 2006
Vaughan P Wittman David Woodburn Tiffany Nguyen Francisca A Neethling Stephen Wright Jon A Weidanz

Therapeutic mAbs that target tumor-associated Ags on the surface of malignant cells have proven to be an effective and specific option for the treatment of certain cancers. However, many of these protein markers of carcinogenesis are not expressed on the cells' surface. Instead these tumor-associated Ags are processed into peptides that are presented at the cell surface, in the context of MHC c...

امینی نجفی, فاطمه, حسینی, سیدکاظم, حیدرنسب, داریوش, خسروی, علیرضا, صفری, زهرا, علیزاده, علی‌محمد, محمودی, مجید,

Background: Fumonisins, a family of mycotoxins, are mainly found in wheat, corn and their products. Previous studies have shown that fumonisin B1 (FB1), the most abundant and toxic of known fumonisins, has been associated with many animal and human diseases including cancer. In the present study, the effects of FB1 were examined on the production of inflammatory cytokines in intestine and stoma...

2005
R. B. Armenta M. J. Barnes E. W Blackmore O. Hadary L. Ahrens C. J. Gardner W. Zhang

Knoxville, May 16–20 May 2005 DESIGN CONCEPT FOR AGS INJECTION KICKER UPGRADE TO 2 GEV* R.B. Armenta, M.J. Barnes, E.W Blackmore, O. Hadary, G.D. Wait, TRIUMF, Vancouver, B.C., L. Ahrens, C.J. Gardner, W. Zhang, Brookhaven National Laboratory, Upton, NY Abstract The present AGS injection kickers at A5 location were designed for 1.5 GeV proton injection. Recent high intensity runs have pushed th...

2011
L. Ahrens K. Brown J. Glenn H. Huang F. Méot T. Roser V. Schoefer N. Tsoupas

A model of the Alternating Gradient Synchrotron is being developed based on stepwise ray-tracing numerical tools. It provides a realistic representation of the lattice, and accounts for the two helical partial Siberian snake insertions. The aim is to make this stepwise ray-tracing based model an aid for the understanding of the AGS, in matter of both beam dynamics and polarization transmission....

Journal: :Journal of immunology 2014
Sachiko Hirosue Efthymia Vokali Vidya R Raghavan Marcela Rincon-Restrepo Amanda W Lund Patricia Corthésy-Henrioud Francesca Capotosti Cornelia Halin Winter Stéphanie Hugues Melody A Swartz

Until recently, the known roles of lymphatic endothelial cells (LECs) in immune modulation were limited to directing immune cell trafficking and passively transporting peripheral Ags to lymph nodes. Recent studies demonstrated that LECs can directly suppress dendritic cell maturation and present peripheral tissue and tumor Ags for autoreactive T cell deletion. We asked whether LECs play a const...

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