نتایج جستجو برای: adverse event reporting

تعداد نتایج: 485155  

2012
Kaori Kadoyama Ikuya Miki Takao Tamura JB Brown Toshiyuki Sakaeda Yasushi Okuno

OBJECTIVE The safety profiles of oral fluoropyrimidines were compared with 5-fluorouracil (5-FU) using adverse event reports (AERs) submitted to the Adverse Event Reporting System, AERS, of the US Food and Drug Administration (FDA). METHODS After a revision of arbitrary drug names and the deletion of duplicated submissions, AERs involving 5-FU and oral fluoropyrimidines were analyzed. Standar...

2011
Toshiyuki Sakaeda Kaori Kadoyama Hiroaki Yabuuchi Satoshi Niijima Kyoko Seki Yukinari Shiraishi Yasushi Okuno

OBJECTIVE Adverse event reports (AERs) submitted to the US Food and Drug Administration (FDA) were reviewed to confirm the platinum agent-associated mild, severe, and lethal hypersensitivity reactions. METHODS Authorized pharmacovigilance tools were used for quantitative signal detection, including the proportional reporting ratio, the reporting odds ratio, the information component given by ...

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