Introduction: Gangliogliomas are rare neuroepithelial tumours that account for only 0.4% of the CNS tumours hence no prospective studies are done regarding the management. This case report describes management of ganglioglioma and use of radiotherapy in the adjuvant setting. Case Description: An eight year old girl presented with complaints of seizures and after evaluation underwent craniotomy ...

Purpose. Transoral robotic surgery (TORS) has increased in popularity in the management of squamous cell carcinoma of the head and neck. However, TORS does not address the neck or retropharyngeal nodes (RPN). In the current report, we highlight the impact of the lack of adjuvant radiotherapy on RPN recurrence after TORS. Materials and Methods. A 58-year-old Caucasian male presented with squamou...

OBJECTIVE To study the efficacy of different locoregional treatment options for tongue cancer in determining the prognosis, with reference to recurrence of disease in neck. METHODS This is a retrospective analysis of 80 patients with early (T1/T2) carcinoma tongue who had hemiglossectomy with or without neck surgery and radiotherapy for 14 years. RESULTS Eighty patients were included in thi...

solitary plasmacytoma of bone is a rare malignant tumor mostly involving the axial skeleton. the tumor occurs in middle- aged or elderly people (mean age: 55 years) and has a high risk of progression to multiple myeloma. radiotherapy is the preferred treatment for this disease. we report a case of recurrent solitary plasmacytoma of the fourth lumbar vertebra in a 35-year-old male. the patient s...

OBJECTIVE To evaluate the effect of time between surgery and postoperative radiation therapy on local recurrence of squamous cell carcinoma of the tongue and floor of the mouth. METHODS A total of 154 patients treated between 1996 and 2007 were selected considering local recurrence rate and time of the adjuvant radiotherapy. RESULTS Local recurrence was diagnosed in 54 (35%) patients. Radia...

Although protracted cognitive impairment has been reported to occur after radiotherapy even when such therapy is not directed to brain areas, the mechanism remains unclear. This study investigated whether breast cancer patients exposed to local radiotherapy showed lower cognitive function mediated by higher plasma interleukin (IL)-6 levels than those unexposed. We performed the Wechsler Memory ...

BACKGROUND Single nucleotide polymorphisms (SNPs) in a DNA-repair gene, X-Ray repair cross complementing group 1 (XRCC1), have been associated with the survival of patients with breast cancer. We investigated the predictive value of XRCC1 SNP (rs25487) in patients with early breast cancer. PATIENTS AND METHODS The XRCC1 rs25487 genotypes of 411 Finnish patients with breast cancer were analyze...

Myxopapillary ependymoma (MPE) is a World Health Organization grade I ependymoma that is quite rare and generally thought to be benign. Possible drop metastasis from MPE has been reported three times in the literature; in each case there were cotemporaneous additional MPE lesions. We report the case of a man who had a piecemeal gross total resection of a MPE at L1-L3 followed by adjuvant extern...

Radical prostatectomy and radiotherapy remain the most popular treatments for localized prostate cancer.[1] In the most recent updated iteration of the Partin Tables, approximately 24% of patients undergoing prostatectomy for clinically localized prostate cancer are predicted to have adverse pathologic findings such as extraprostatic extension (EPE) or seminal vesicle invasion (SVI), and as man...