نتایج جستجو برای: adipor1
تعداد نتایج: 393 فیلتر نتایج به سال:
PURPOSE The incidence of benign prostatic hyperplasia increases among obese individuals, but few studies have fully explained the underlying mechanisms. Adiponectin has drawn much attention in recent years due to its protective role in obesity-related diseases. Here we aimed to investigate the possible molecular mechanisms and clinical significance of adiponectin in relation to benign prostatic...
The World Health Organization estimates that the number of obese and overweight adults has increased to 1.6 billion, with concomitant increases in comorbidity. While genetic factors for obesity have been extensively studied in Caucasians, fewer studies have investigated genetic determinants of body mass index (BMI; weight (kg)/height (m)(2)) in African Americans. A total of 38 genes and 1,086 s...
Adiponectin is an adipocyte-derived hormone that can improve insulin sensitivity. Its functions in regulating glucose utilization and fatty acid metabolism in mammals are mediated by 2 subtypes of adiponectin receptors (AdipoR1 and AdipoR2). This study was conducted to determine the effect of fasting on the expression of adiponectin and its receptors. The expression of adiponectin was not affec...
Adiponectin is an adipocyte-derived hormone that acts as a major regulator of energy metabolism and insulin sensitivity (1, 2). In plasma, adiponectin occurs in different forms: the trimeric low molecular weight (LMW), the hexameric middle molecular weight (MMW) and the 12-18meric high molecular weight (HMW) complexes (3). Adiponectin can be found in a smaller globular form, which is produced t...
background: endometriosis is a complex disorder in reproductive age women which consist of stromal and epithelial cells implantation outside the uterine cavity. adiponectin is a member of cytokine family with various metabolic roles and proliferation inhibition of many cancer cells. the aim of the present research was to determine adiponectin effect on human endometriotic stromal cells (escs) p...
Adipose tissue in abdominal obesity produces various cytokines, the most important of which is adiponectin (AN). Polymorphism AN receptor genes associated with risk metabolic syndrome (MS) and type 2 diabetes mellitus (DM2) development. The aim study was to investigate association receptors’ polymorphism development MS DM2 Republic Crimea as well possibility named pathology correction polypheno...
BACKGROUND Reproductive dysfunction in the diabetic female rat is associated with altered folliculogenesis and steroidogenesis. However, the molecular mechanisms involved in the reduction of steroid production have not been described. Adiponectin is an adipocytokine that has insulin-sensitizing actions including stimulation of glucose uptake in muscle and suppression of glucose production in li...
مقدمه و هدف: آدیپونکتین ، فعالیت ضد سرطانی خود را از طریق اتصال به گیرنده ا ش انجام می دهد. مطالعات نشان داده اند که پلی مورفیسم در گیرنده آدیپونکتین باعث مقاومت به انسولین، دیابت نوع 2 و سرطان روده ی بزرگ می شود. هدف از این مطالعه، ارزیابی میزان شیوع آلل موتانت پلی مورفیسم گیرنده ی 1 آدیپونکتین 2275738 rs در یک جمعیت از ایران و بررسی نقش این پلی مورفیسم در افزایش خطر ابتلا به سرطان روده بزرگ ا...
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