Wnt-11/planar cell polarity signaling polarizes mesodermal cells undergoing convergent extension during Xenopus laevis gastrulation. These shape changes associated with lateral intercalation behavior require a dynamic modulation of cell adhesion. In this paper, we report that Wnt-11/frizzled-7 (Fz7) controls cell adhesion by forming separate adhesion-modulating complexes (AMCs) with the paraxia...

BACKGROUND Tension pneumothorax is a life-threatening occurrence that is infrequently the consequence of spontaneous pneumothorax. The aim of this study was to identify the risk factors for the development of tension pneumothorax and its effect on clinical outcomes. METHODS We reviewed patients who were admitted with spontaneous pneumothorax between August 1, 2003 and December 31, 2011. Elect...

BACKGROUND Adhesion formation results from a series of local events at the trauma site. This process can be enhanced by factors derived from the peritoneal cavity such as mesothelial cell hypoxia (pneumoperitoneum with pure CO(2)), reactive oxygen species (pneumoperitoneum with more than 4% oxygen), desiccation and mesothelial trauma produced through manipulation. Adhesion prevention, therefore...

background: postoperative peritoneal adhesion bands are one of the most common complications caused by foreign material.   objective: to investigate the effect of colchicine on talc-induced peritoneal adhesion bands.   method: adhesion bands were induced in 30 short hair england guinea pigs by introduction of talc-saline solution (10 ml, 10%) into the peritoneal cavity.  afterwards, the pigs we...

The factors determining the adhesive strength of film coatings are considered. functions contacts in thermoelements used a wide temperature range were determined. It was established that contact is limiting factor mechanical thermoelement. A method vacuum sputtering thin-film proposed, including surface treatment samples thermoelectric materials. presence transition layer area metal-thermoelect...

Exchanges between the blood compartment and the surrounding tissues require a tight regulation by the endothelial barrier. Recent reports inferred that VE-cadherin, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. Indeed, a growing number of permeability inducing factors (PIFs) was shown to elicit signali...

The epithelial-mesenchymal transition is essential in both embryonic development and the progression of carcinomas. Wnt signaling and cadherin-mediated adhesion have been implicated in both processes; clarifying their role will depend on linking them to rearrangements of cellular structure and behavior. beta-Catenin is an essential molecule both in cadherin-mediated cell adhesion and in canonic...