ADAMs (a disintegrin and metalloproteinase) are sheddases possessing extracellular metalloproteinase/disintegrin/cysteine-rich (MDC) domains. ADAMs uniquely display both proteolytic and adhesive activities on the cell surface, however, most of their physiological targets and adhesion mechanisms remain unclear. Here for the first time, we reveal the ADAMs' MDC architecture and a potential target...

In this study, both theoretical linear model and numerical model are used to predict and optimize the frequencies of shimmy related modes and the level of the vibration for a vehicle. A theoretical multi-body linear model of 32-DOF were used for quasi-static analysis and modal analysis. The theoretical model was verified by comparing the results of modal analysis with those of modal test for fr...

How far the stability domain of a numerical method for approximating solutions to differential equations extends along the imaginary axis indicates how useful the method is for approximating solutions to wave equations; this maximum extent is termed the stability ordinate, also known as the imaginary stability boundary. It has previously been shown that exactly half of Adams-Bashforth, Adams-Mo...

A structural measurement model (Adams, Wilson, & Wu, 1997) consists of an item response theory model for responses conditional on ability and a structural model that describes the distribution of ability in the population. As a rule, ability is assumed to be normally distributed in the population. However, there are situations where there is reason to assume that the distribution of ability is ...

In this paper we attempt to analyze and simulate the windshield wiper mechanisms, using the multibody systems software ADAMS. The design algorithm involves three mechanical models: kinematic model – to performe the positional analysis of the wiper system, inverse dynamic model – to determine the torque applied to the motor crank in order to generate the kinematically-prescribed behavior, and dy...

Developed Navier-Stokes turbulence is simulated with varying wave-vector mode reductions. The flatness and the skewness of the velocity derivative depend on the degree of mode reduction. They show a crossover towards the value of the full numerical simulation when the viscous subrange starts to be resolved. The intermittency corrections of the scaling exponents zp of the pth order velocity stru...