Background: Blood transfusion is a life-saving but high-risk procedure in various medical conditions as it not simple fluid infusion an organ transplant. Although blood transfusions save lives, they may cause serious, life-threatening reactions. Nowadays, the number of reactions has decreased significantly with reduction leucocyte content products or their irradiation. 
 Materials and Meth...

We attempt to analyze and adopt the interference of monoclonal antibody cluster differentiation 38 on ABO blood group identification cross-matching. Search PubMed, Medline, Web Science, China National Knowledge Infrastructure, Wanfang other domestic foreign databases, screening patients requiring transfusion after receiving anti-cluster antibody, retrospective analysis anti-human globulin casse...

Background/Objectives. Blood transfusion is a critical issue for patients with chronic diseases such as heart failure, chronic kidney disease, and malignancy. However, side effects are not rare. The purpose of the study is to evaluate the frequency of adverse blood transfusion reactions in hospitalized elderly patients during a one-year period. Design/Setting/Participants. Blood transfusion rea...

We report an Rh(D)-negative man with myelodysplastic syndrome who produced six anti-erythrocyte alloantibodies (anti-D, -C, -E, -Dia, -Jka and -S) in succession. Three of these antibodies (anti-E, -Jka and -S) were not noted until delayed hemolytic transfusion reactions occurred. Treatment with cortico-steroids was effective in preventing both further formations of antibodies and other transfus...

BACKGROUND Anti-IH is usually a clinically insignificant antibody that may complicate a serologic workup. However, it can occasionally cause hemolysis. We report a rare case of acute hemolysis caused by anti-IH. CASE REPORT A 60-year-old man with a long history of chronic myelomonocytic leukemia and anemia, blood group A, D+ was found to have an unidentified antibody on serologic workup. He r...

Red blood cell transfusions are used to treat hemorrhage and to improve oxygen delivery to tissues. Transfusion of red blood cells should be based on the patient's clinical condition. Indications for transfusion include symptomatic anemia (causing shortness of breath, dizziness, congestive heart failure, and decreased exercise tolerance), acute sickle cell crisis, and acute blood loss of more t...

BACKGROUND Platelet component (PC) transfusion leads occasionally to inflammatory hazards. Certain BRMs that are secreted by the platelets themselves during storage may have some responsibility. METHODOLOGY/PRINCIPAL FINDINGS First, we identified non-stochastic arrangements of platelet-secreted BRMs in platelet components that led to acute transfusion reactions (ATRs). These data provide form...

Preoperative autologous blood donation (PABD) can be an adequate solution to a patient’s problem before nonurgent surgery if a high (>10%) probability of perioperative blood transfusion exists in this individual case and, at the same time, pre-existing alloimmunization or a different ethnic background make it difficult to supply this patient with compatible red blood cell concentrates. In times...

Original Article Background: In 30 patients with denovo acute myeloid and lymphoid leukemia (FAB classification), we compared the effectiveness of RBC and Platelet transfusion and the relation to increment of the transfused component was analyzed. Materials and Methods: This study was conducted in the Department of hematology, Institute of Child Health for a period of one year. All acute leukem...