نتایج جستجو برای: acute lymphocytic leukemia
تعداد نتایج: 694854 فیلتر نتایج به سال:
By DANE R. BOGGS T HE NATURE of the defect in host defense mechanisms resulting in the increased incidence of bacterial infection in the leukemias is ill defined. Studies of antibody formation indicate that the patient with an acute leukemia or with chronic myelocytic leukemia has normal or near normal response to antigenic stimulation, whereas the patient with chronic lymphocytic leukemia freq...
PURPOSE DX-8951f is a novel hexacyclic camptothecin-analogue topoisomerase I inhibitor with both in vitro antileukemic activity and myelosuppression as a dose-limiting toxicity in solid tumor Phase I studies. DX-8951f is active in a human acute myeloid leukemia (AML) severe combined immunodeficient mouse model. In a leukemia Phase I study, we investigated the toxicity profile and pharmacokineti...
Bone marrow transplantation has become the accepted treatment for several hematologic disorders. We have done 3 autologous and 6 allogeneic bone marrow transplantations at Ramathibodi Hospital since July 1989 in patients with acute lymphoblastic leukemia, acute non-lymphocytic leukemia, chronic myeloid leukemia, non-Hodgkin's lymphoma and severe aplastic anemia. Only one patient with aplastic a...
Chronic lymphocytic leukemia is a disease with up-regulated expression of the transmembrane tyrosine-protein kinase ROR1, a member of the Wnt/planar cell polarity pathway. In this study, we identified COBLL1 as a novel interaction partner of ROR1. COBLL1 shows clear bimodal expression with high levels in chronic lymphocytic leukemia patients with mutated IGHV and approximately 30% of chronic ly...
Despite recent advances in the treatment of acute leu kemia in man (13, 14, 16, 19), most patients die of recurrent leukemia (10). Chemotherapy usually is much less effective when used following relapse of leukemia after an initial remission and, with only occasional exceptions, sustained subsequent remissions do not occur (1). The experiments described below were performed in order to test a s...
The French-American-British (FAB) and WHO classifications provide important guidelines for the diagnosis, treatment, and prognostic prediction of acute leukemia, but are incapable of accurately differentiating all subtypes, and not well correlated with the clinical outcomes. In this study, we performed the protein profiling of the bone marrow mononuclear cells from the patients with acute leuke...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید