This study describes the characteristics of 31 children with congenital toxoplasmosis children admitted to the University Hospital of Londrina, Southern Brazil, from 2000 to 2010. In total, 23 (85.2%) of the mothers received prenatal care but only four (13.0%) were treated for toxoplasmosis. Birth weight was <2500g in 37.9% of the infants. During the first month of life, physical examination wa...

This article presents a review of the recommendations on supplementary exams employed for the clinical diagnosis of Alzheimer's disease (AD) in Brazil published in 2005. A systematic assessment of the consensus reached in other countries, and of articles on AD diagnosis in Brazil available on the PUBMED and LILACS medical databases, was carried out. Recommended laboratory exams included complet...

Precise control of self-renewal and differentiation of progenitor cells into the cranial neural crest (CNC) pool ensures proper head development, guided by signaling pathways such as BMPs, FGFs, Shh and Notch. Here, we show that murine Sox2 plays an essential role in controlling progenitor cell behavior during craniofacial development. A "Conditional by Inversion" Sox2 allele (Sox2(COIN) ) has ...

Key words Disease name Definition Excluded diseases Epidemiology Clinical description Diagnostic methods Etiology Genetic counseling Antenatal diagnosis Management including treatment Prognosis References Abstract Porencephaly is a circumscribed intracerebral cavity of variable size which may be bordered by abnormal polymicrogyric grey matter. In extreme cases, this cavity may result in a commu...

Kidney function requires the appropriate distribution of membrane proteins between the apical and basolateral surfaces along the kidney tubule. Further, the absolute amount of a protein at the cell surface versus intracellular compartments must be attuned to specific physiological needs. Endolyn (CD164) is a transmembrane protein that is expressed at the brush border and in apical endosomes of ...

the toxicity of 7 herbicides to the three cyanobacteria was tested in this work. the results indicated that: (1) there was a highly significant relationship between dried weight or chlorophyll-a and od680nm for tested cyanobacteria; (2) the toxicity of the tested herbicides with the order from high to low was: photosynthesis-inhibiting > accase inhibitor > protox inhibiting herbicides; (3) the ...

introduction hemangioma is the most common benign tumor of the liver. most cases are asymptomatic and do not require treatment. a hemangioma can rarely be pedunculated; as a result, it may undergo torsion and infarction, which can make it symptomatic. case presentation we report the case of a 45-year-old woman with acute abdominal pain due to torsion of a giant pedunculated hepatic hemangioma a...

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acute bacterial meningitis (abm) is one of the most severe infectious diseases, causing neurologic sequel, and a case fatality rate of 20-30%. the aim of this paper was to summarize the main causes of abm in iran. we searched the data for relevant articles using meningitis, etiology, and iran as search terms. we found 23 papers for inclusion in the review that focused specifically on the abm, a...

background: the purpose of this study was to examine symptoms of acute coronary syndrom (acs) with resect to sex differences. methods: this comparative cross-sectional study was performed on patients older than 20 years with acs who were hospitalized at cardiac wards. sampling was performed through stratified sampling on the basis of sex. five hundred male and female patients met all eligiblity...