Background: Rotavirus infection is a major cause of diarrhea in children under five years of age in both the developed and developing countries. Rotavirus is often associated with acute infection with high severity level that causes death. The rotavirus genotype, patient immunity, and environmental condition are thought to be related to the severity of the incidence of acute diarrhea due to rot...

Subcutaneous challenge of mice with lipopolysaccharide (LPS) from gram negative bacteria, produced an intestinal microvascular lesion causing fluid exudation into the lumen of the intestine and diarrhea. The microvascular lesion was characterized by endothelial cell damage and microthrombi in the venules and capillaries of the intestinal lamina propria. Marker organisms, given orally to challen...

BACKGROUND Acute diarrhea is a global health problem, resulting in high morbidity and mortality in children. It has been suggested that enteric pathogen co-infections play an important role in gastroenteritis, but most research efforts have only focused on a small range of species belonging to a few pathogen groups. This study aimed to assess the impact of co-infections with a broad range of en...

AIM The aim of this study is to assess the sensitivity and specificity of procalcitonin to determine bacterial etiology of diarrhea. THE EXAMINEES AND METHODS For this purpose we conducted the study comprising 115 children aged 1 to 60 months admitted at the Department of Pediatric Gastroenterology, Pediatric Clinic, divided in three groups based on etiology of the diarrhea that has been conf...

During the past 1 5 years, oral rehydration therapy has been extensively and increasingly used in developing countries for the treatment of dehydration in acute infantile diarrhea.1 It has been shown that mortality from this disease, which is the leading cause of infant deaths in developing countries, can be reduced dramatically by using oral rehydration 2 Despite this experience, many physicia...

INTRODUCTION Acute diarrhea, in the industrialized world, is usually self-limited, infectious in nature, and rarely requires biopsy evaluation. Chronic diarrhea can cause failure to thrive, frequently results in intestinal biopsy and may require parenteral nutrition and other forms of therapy. Protracted diarrhea has replaced the older term “intractable diarrhea” in the GI literature and denote...