We describe a patient with a serious urinary tract infection due to Actinomyces bernardiae (formerly classified as CDC [Centers for Disease Control and Prevention, Atlanta] fermentative coryneform group 2). Our patient had long-standing bladder dysfunction and developed hydroureteronephrosis, renal lithiasis, perirenal abscesses, and septicemia. A. bernardiae is distinct from Actinomyces pyogen...

Actinomyces spp., predominant members of human oral biofilms, may use extracellular sialidase to promote adhesion, deglycosylate immunoglobulins and liberation of nutrients. Partial nanH gene sequences (1,077 bp) from Actinomyces oris (n=74), Actinomyces naeslundii (n=30), Actinomyces viscosus (n=1) and Actinomyces johnsonii (n=2) which included the active-site region and the bacterial neuramin...

Interbacterial adherence was sought between strains of Actinomyces viscosus indigenous to the human mouth and strains of Streptococcus pyogenes, Streptococcus agalactiae, and Pseudomonas aeruginosa. Six of nine strains of S. pyogenes, three of five strains of S. agalactiae, and two of four strains of P. aeruginosa were found to coaggregate with each of five strains of A. viscosus tested. Some c...

This paper describes the purification of two antibiotic substances produced by strains of Actinomyces isolated from soil. Both organisms were isolated and studied by Dr. Albert Iielner of the University of Pennsylvania for their cultural characteristics and conditions for maximum production of the antibiotic substances. Animal experiments, determination of antibacterial spectrum, etc., were con...

Amplified 16S ribosomal DNA (rDNA) restriction analysis (ARDRA), using enzymes HaeIII and HpaII, was applied to 176 fresh and 299 stored clinical isolates of putative Actinomyces spp. referred to the Anaerobe Reference Unit of the Public Health Laboratory Service for confirmation of identity. Results were compared with ARDRA results obtained previously for reference strains and with conventiona...

Members of the genus Actinomyces are strongly associated with human diseases. We present here the complete genome sequence of Actinomyces hongkongensis HKU8T, which consists of one circular chromosome. The strain characteristically contains various genes encoding for enzymes involved in arylamidase utilization.

A previous observation, using a few representative laboratory strains, that rabbit antisera raised against isolated surface fibrils might be useful in identifying Actinomyces viscosus and Actinomyces naeslundii isolates to their correct numerical taxonomy clusters was reexamined with a large culture collection, including clinical isolates from three different laboratories. Strains were first id...

This is the first report of Actinomyces europaeus bacteraemia in a 53-year-old man. The bacteraemia was the result of a breast abscess. Identification was established by matrix-assisted desorption ionization-time of flight mass spectrometry and confirmed by 16S rRNA gene sequencing. The patient was treated with surgical drainage and penicillin for 4 weeks; the patient did not experience any rel...

Abstract Actinomyces europaeus is a sub-species of actinomyces first isolated in humans 1997. It commensal bacteria found within the genitourinary and gastrointestinal tract. Although it known to cause soft tissue infection has been abscesses, never identified as primary pathogen case necrotizing fasciitis. We present 59-year-old man with recurrent groin infections, poorly controlled Type 2 dia...

One of the most important tasks in our present day science of antibiotics is the establishment of a completely rational taxonomy and nomenclature for antibiotic-producing organisms. A purposeful search for antibiotic substances is possible only with good knowledge of the species which produce them. A great many antibiotic-producing actinomycetes have been described recently. Investigators often...